河北医科大学学报 ›› 2025, Vol. 46 ›› Issue (7): 802-807.doi: 10.3969/j.issn.1007-3205.2025.07.010

• • 上一篇    下一篇

血管内超声指导冠状动脉小血管疾病药物球囊的临床应用

  

  1. 河北医科大学第二医院鹿泉院区心血管内科，河北 石家庄 050200

  • 出版日期:2025-07-25 发布日期:2025-07-24
  • 作者简介:刘玉龙（1990-），男，河北邢台人，河北医科大学第二医院鹿泉院区主治医师，医学硕士，从事心血管内科疾病诊治研究。
  • 基金资助:
    河北省医学科学研究课题计划（20220988）

Clinical application of intravascular ultrasound-guided drug-coated balloons in small-vessel coronary artery disease

  1. Department of Cardiovascular Medicine, Luquan Branch of the Second Hospital of Hebei Medical University, Shijiazhuang 050200, China

  • Online:2025-07-25 Published:2025-07-24

HTML

PDF (PC)

24

摘要： 目的 分析血管内超声（intravascular ultrasound，IVUS）指导冠状动脉小血管疾病（small vessel coronary artery disease，SVD）药物球囊（drug-coated balloons，DCB）的临床应用效果。
方法 回顾性分析2020年6月—2022年6月在河北医科大学第二医院住院的不稳定型心绞痛患者284例，其中IVUS指导组（IVUS组）142例，单纯冠状动脉造影（coronary angiography，CAG）指导组（CAG组）142例。比较IVUS和单纯CAG评估DCB治疗SVD的即刻及远期影像学结果及临床事件。
结果 IVUS作为一种高分辨率的图像引导技术，能够比CAG提供更详细的血管内部结构信息。结果显示，IVUS组较CAG组，预处理球囊直径更大［（2.38±0.25）mm vs. (2.25±0.34)mm，P＜0.05］，预扩张更充分，即刻残余狭窄率更低［（13.18±6.40)% vs. (16.74±6.55)%，P＜0.05］,DCB直径更大［（2.46±0.25)mm vs. (2.24±0.33)mm，P＜0.05］，长度更长［（24.09±4.84)mm vs. (21.67±4.08)mm，P＜0.05］，远期残余狭窄程度更低［（8.22±10.66)% vs. (16.39±13.66）%,P＜0.05］。
结论 IVUS指导DCB治疗SVD较单纯CAG指导具有更好的影像学及临床效果。


关键词: 心绞痛, 不稳定型, 冠状血管, 超声检查, 药物球囊

Abstract: Objective To analyze the clinical application effect of intravascular ultrasound (IVUS)-guided drug-coated balloons (DCB) in the treatment of small-vessel coronary artery disease (SVD). 
Methods A retrospective analysis was conducted on 284 patients with unstable angina hospitalized at the Second Hospital of Hebei Medical University from June 2020 to June 2022. Patients were divided into two groups: the IVUS-guided group (IVUS group, n=142) and the coronary angiography (CAG)-guided group (CAG group, n=142). Immediate and long-term imaging outcomes and clinical events of DCB treatment for SVD between IVUS and simple CAG evaluation were compared. 
Results IVUS, as a high-resolution imaging technique, provided more detailed vascular structural information than CAG. The IVUS group demonstrated larger pre-treatment balloon diameter ［(2.38±0.25) mm vs. (2.25±0.34) mm, P＜0.05］, more sufficient pre-dilation, including lower immediate residual stenosis ［(13.18±6.40)% vs. (16.74±6.55)%, P＜0.05］, larger DCB diameter ［(2.46±0.25) mm vs. (2.24±0.33) mm, P＜0.05］, longer DCB length ［(24.09±4.84) mm vs. (21.67±4.08) mm, P＜0.05］, and reduced long-term residual stenosis ［(8.22±10.66)% vs. (16.39±13.66)%, P＜0.05］. 
Conclusion IVUS-guided DCB for the treatment of SVD yields superior imaging and clinical outcomes compared with CAG guidance alone. 


Key words: angina, unstable, coronary vessels, ultrasonography, drug-coated balloons

版权所有 © 《河北医科大学学报》编辑部
本系统由北京玛格泰克科技发展有限公司设计开发