关键词: 房间隔缺损, 经皮封堵术, 妊娠, 心脏功能, 二维应变

Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate of right heart function by twodimensional strain imaging in pregnant women after transcatheter closure of atrial septal defect.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Using twodimensional strain imaging，the right ventricular free wall base, middle sections of longitudinal peak systolicvelocities(strain of systole,S)，early diastolic peak strain rate（strain rate of early diastolic,SRe）, late diastolic peak strain rate(strain rate of atrial systole,SRa),SRe/SRa were calculated repeatedly in 25 pregnant women after transcatheter closure(PASD group),and 25 healthy pregnant women as controls(control group). Diameter of the right atrium and right ventricular, pulmonary artery systolic pressure estimated by tricuspid regurgitation velocity, right ventricular enddiastolic volume， right ventricular endsystolic volume, right vertricular ejection fraction were calculated.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Inner diameter of the right ventricular and pulmonary artery systolic pressure of two groups increased gradually over time. There were significant difference between the two groups, between time point, and between group & time point（P＜005）. SRe/SRa of base, middle sections in PASD group and control group showed decreasingly trend with the increase in pregnancy, and there were significant difference between the two groups, between time point, and between group & time point（P＜005）.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The parameters of right heart function in pregnant women after transcatheter closure of atrial septal defect had showed some significant change, especially by twodimensional strain imaging. The pregnant women which have the history transcatheter closure of atrial septal defect need to focus on their PASP and parameters of right heart function in duration of pregnancy.

Key words: atrial septal defect, percutaneous transcatheter closure, pregnancy, cardiac function, twodimensional strain