河北医科大学学报

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脉冲染料激光治疗新生儿期婴幼儿血管瘤的效果观察

  

  1. 1.河北省儿童医院整形外科，河北 石家庄 050031；2.河北省儿童医院儿研所，河北 石家庄 050031
  • 出版日期:2017-07-25 发布日期:2017-07-05
  • 作者简介:张文显（1962-），男，河北石家庄人，河北省儿童医院副主任医师，从事儿童体表肿瘤及先天畸形诊治研究。
  • 基金资助:
    河北省医学科学研究重点课题（20170408）

Effect of pulsed dye laser therapy on infantile hemangioma during neonatal period

  1. 1.Department of Plastic Surgery, Children's Hospital of Hebei Province， Shijiazhuang 050031， China；
    2.Institute of Pediatrics, Children's Hospital of Hebei Province， Shijiazhuang 050031， China
  • Online:2017-07-25 Published:2017-07-05

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摘要： 摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨脉冲染料激光治疗新生儿期婴幼儿血管瘤的有效性与可行性。
〖HTH〗方法〖HTSS〗〖KG*2〗应用脉冲染料激光治疗婴幼儿血管瘤患儿1 881例。依年龄划分为新生儿组（年龄≤28 d）93例和非新生儿组（年龄＞28 d）1 788例，比较2组的临床资料。
〖HTH〗结果〖HTSS〗〖KG*2〗新生儿组临床疗效优于非新生儿组（P＜005）。新生儿组治疗后疗效评分高于非新生儿组，单次治疗能量、总治疗能量高于非新生儿组（P＜005）。2组总治疗次数差异无统计学意义(P＞005)。
〖HTH〗结论〖HTSS〗〖KG*2〗特定参数的脉冲染料激光治疗新生儿期婴幼儿血管瘤是安全、有效和可行的。相较于非新生儿期的患儿，在新生儿期进行治疗效果良好。

关键词: 血管瘤, 激光, 染料, 婴儿, 新生

Abstract: ［Abstract］  Objective〖HTSS〗〓To study the feasibility and validity of pulsed dye laser(PDL) for treating infantile hemangionma(IH) in neonates.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓All patients were diagnosed as infantile hemangionmas and were divided to neonate group(younger than 28days, 93 patients) and nonneonate group(older than 28 days, 1 788 patients). Their clinical data were collected, and the treatment outcomes and PDL parameters in neonates and nonneonates were analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The neonates group shows a better therapy result than nonneonatal group(P＜005). Laser energy used per treatment session was signifcantly lower in neonatal group than in nonneonatal group(P＜005). Total laser energy used in neonates was also markedly lower than the control group(P＜005). However, treatment session numbers in these two groups were no significant difference(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓PDL, with distinct parameters, is a safe, feasible and effective treatment method for the therapy of IH in neonates. After each laser treatment, neonates has a better treatment result and recovered faster than nonneonatal patients.

Key words: hemangioma, lasers, dye, infant, newborn

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