关键词: 地佐辛, 麻醉, 全身, 腹腔镜

Abstract: ［Abstract］ Objective〖HTSS〗〓To evaluated dezocine for preventing catheterrelated bladder discomfort(CRBD) after laparoscopic surgery in general anesthesia.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓 Forty  patients(ASA ⅠorⅡ)undergoing laparoscopic radical gastrectomy were randomly divided into two groups:dezocine group(group D) and control group(group C), 20 cases in each. Group D received dezocine  0.1 mg/kg, or group C received normal saline 2 mL 20 min before the end of operation. The operation time,the consciousness recovery time and extubation time were recorded. The MAP, HR and SpO2 were recorded after the surgery(T1), during extubation(T2), 5 min(T3) and 10 min after extubation(T4), respectively. In the postanesthesia care unit severity of CRBD and sedation  scale was assessed,the incidence of the adverse reaction were also compared.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The two groups of MAP and HR were all increased first and then decreased,and SpO2 was downward trend. MAP, HR and SpO2 had statistically significant differences in two groups compared with groups, different time points and groups·time points(P＜005). The severity of CRBD in group D was reduced significantly compared with those in group C （P＜005）, Ramsay sedation scale at extubation later was better in group D than that in group C(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Dezocine can effectively prevention CRBD after laparoscopic surgery in general anesthesia and maintain hemodynamic stability.

Key words: dezocine, anesthesia, general, laparoscopes