河北医科大学学报

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结核性脑膜炎临床和影像学特征与临床分期的相关性分析

  

  1. 1.河北省胸科医院神经内科，河北 石家庄 050041；2.河北省胸科医院急诊科，河北 石家庄 050041
  • 出版日期:2018-07-25 发布日期:2018-07-04
  • 作者简介:李军霞（1984-），女，河北石家庄人，河北省胸科医院主治医师，医学硕士，从事神经内科疾病诊治研究。
  • 基金资助:
    河北省医学科学研究重点课题（20150139）

The correlation between the clinical manifestations and imaging findings of tuberculous meningitis and different clinical stages#br#

  1. 1.Department of Neurology, Hebei Chest Hospital, Shijiazhuang 050041, China； 
    2.Department of Emergency, Hebei Chest Hospital, Shijiazhuang 050041, China
  • Online:2018-07-25 Published:2018-07-04

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摘要： ［摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨结核性脑膜炎的临床表现和MRI增强扫描结果与其对应MRC分期之间的相关性。
〖HTH〗方法〖HTSS〗〖KG*2〗对85例结核性脑膜炎患者进行MRC分期，收集其临床表现及MRI增强扫描结果，并进行相关性分析。
〖HTH〗结果〖HTSS〗〖KG*2〗MRC分期与颅内压增高及脑膜刺激征、脑实质受损、脑神经损害呈正相关（P＜005），与结核中毒症状无相关（P＞005）。MRC分期与脑膜病变、结核性脑脓肿、并发症呈正相关（P＜005），与局部脑炎、结核球、无异常无相关（P＞005）。
〖HTH〗结论〖HTSS〗〖KG*2〗结核性脑膜炎MRC分期越靠后，症状越重，脑膜越容易受累，结核性脑脓肿及颅内并发症越多；结核性脑膜炎MRI增强扫描有特征性表现，对结核性脑膜炎的诊断及病情评估有重要意义。

关键词: 结核, 脑膜, 磁共振成像, 临床表现, 临床分期

Abstract: ［Abstract］〓Objective〖HTSS〗〓To investigate the correlation between the clinical manifestations, imaging findings in contrast enhanced MRI of tuberculous meningitis and the corresponding MRC staging.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓MRC staging was performed in 85 patients with tuberculous meningitis, and their clinical manifestations and MRI enhanced results were collected and analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓MRC staging was positively correlated with increased intracranial pressure and meningeal irritation, cerebral parenchyma damage and brain nerve damage(P＜005), and had no correlation with the symptoms of tuberculosis(P＞005). MRC staging was positively correlated with meningeal disease, tuberculous brain abscess and complications(P＜005), and had no correlation with local encephalitis, tuberculoma and no abnormality(P＞005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The more MRC staging of tuberculous meningitis, the more severe the symptoms, the more vulnerable the meninges, the more tuberculous brain abscess and intracranial complications. The MRI enhanced scan of tuberculous meningitis is characteristic, which is of great significance for the diagnosis of tuberculous meningitis and the evaluation of the disease.

Key words: tuberculosis, meningeal； magnetic resonance imaging； clinical manifestations, clinical stages

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