›› 2015, Vol. 36 ›› Issue (1): 13-13.

• 论文 • 上一篇    下一篇

同期手术治疗非小细胞肺癌胸椎寡转移的临床经验

王东来;冯建刚;李增怀;冯奇;王雷   

  1. 河北医科大学第四医院骨科,河北 石家庄,050011%河北医科大学第四医院胸外科,河北 石家庄,050011
  • 发布日期:2015-01-25

GAO Feng;YAO Min;WANG Xiao-mei;LIU Shu-xia;DUAN Hui-jun

WANG Dong-lai;FENG Jian-gang;LI Zeng-huai;FENG Qi;WANG Lei   

  • Published:2015-01-25

摘要: 目的:探讨同期手术治疗非小细胞肺癌合并胸椎寡转移的方法和疗效。方法回顾性分析非小细胞肺癌单纯胸椎转移患者10例,同期行前路经胸肺癌联合胸椎转移病灶切除,记录手术时间、术中出血量、术后胸腔闭式引流管的拔除时间、术后并发症发生率、术后复发率和生存时间。评估手术方式对患者术前术后疼痛[视觉模拟评分(visual analogue score,VAS)]、神经功能(Frankel分级)和生活质量的改善情况。结果10例单纯胸椎转移灶切除患者的平均手术时间为(348.00±27.48)min,术中出血量(1500.00±547.72)mL,术后胸腔闭式引流的拔出时间(9.00±1.85)d,术后中位生存时间为26个月,术后患者 VAS较术前明显降低(P<0.05),10例中有6例(60.0%)患者 Frankel分级至少降低1级。结论非小细胞肺癌胸椎寡转移患者同期行原发病灶和转移病灶联合切除可以提高患者生存质量,可能会延长患者的生存时间。

关键词: 癌, 非小细胞肺, 胸椎, 肿瘤转移, 外科手术

Abstract: Objective To investigate the techniques and effects of primary and metastatic lesions by simultaneous surgical treatment of non-small cell lung cancer with thoracic oligo metastases.Methods Retrospective analysis was performed on 10 non-small cell lung cancer patients with thoracic oligo metastases who were treated in our hospital.Lobectomy and vetebrectomy by simultaneous operation was performed.Intraoperative and diagnostic data, including perioperative complications,operative time,chest tube length,intraoperative bleeding and survival time were collected using retrospective chart review.The surgical outcomes were assessed according to survival status,neurological function,local recurrence,and pain before and after surgery.Results Ten patients underwent vetebrectomy and lobectomy by one-stage operation of anterior transcavitary approach,the mean operative time was (348.00±27.48)min, intraoperative bleeding (1 500.00± 547.72)mL,chest tube length (9.00± 1.85)d,and median survival time 2 6 months.Neurologic improvement by at least one Frankel grade was noted in 6 of 10 cases (60.0%).The visual analogue score of the patients were significantly reduced after operation(P<0.05).Conclusion The patients of non-small cell lung cancer with thoracic oligo metastases who underwent simultaneous surgical treatment for the primary tumor and thoracic metastatic lesions still have chances to obtain long-term survival.

Key words: carcinoma, non-small-cell lung, thoracic vertebrae, neoplasms metastasis, surgical procedures

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