河北医科大学学报 ›› 2023, Vol. 44 ›› Issue (10): 1205-1209.doi: 10.3969/j.issn.1007-3205.2023.10.015

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DCE-MRI联合CT对布鲁菌病脊柱炎的评估分析

  

  1. 河北北方学院附属第一医院骨科，河北 张家口 075000

  • 出版日期:2023-10-25 发布日期:2023-11-03
  • 作者简介:阴彦林（1971-），男，河北怀安人，河北北方学院附属第一医院副主任医师，医学硕士，从事骨外科疾病诊治研究。
  • 基金资助:
    河北省医学适用技术跟踪项目（GZ2021068）；河北省卫生健康技术研究暨成果转化重点项目（zh2018014）

Analysis on DCE-MRI combined with CT in the evaluation of brucellosis spondylitis

  1. Department of Orthopedics, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China

  • Online:2023-10-25 Published:2023-11-03

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摘要： 目的 应用动态对比增强核磁（dynamic contrast enhancement,DCE-MRI）及电子计算机断层扫描（computer tomography,CT）对高度疑似布鲁菌病脊柱炎（布病脊柱炎）进行诊断，并分析两者联合对布病脊柱炎的诊断价值。
方法 选择河北北方学院附属第一医院收治的高度疑似布病脊柱炎患者80例作为研究对象。所有患者均病理检查及CT、DCE-MRI检查，以病理检查为金标准，分析DCE-MRI联合CT对布病脊柱炎的诊断价值。
结果 80例高度疑似布病脊柱炎患者，经病理诊断，确诊58例为布病脊柱炎组，余22例为非布病脊柱炎组。布病脊柱炎组Ktrans、Kep、Ve高于非布病脊柱炎组（P＜0.05）；DCE-MRI联合CT诊断布病脊柱炎的敏感度、准确度高于DCE-MRI、CT单独诊断（P＜0.05）；CE-MRI联合CT诊断布病脊柱炎的特异度与DCE-MRI、CT单独诊断比较，差异无统计学意义（P＞0.05）。
结论 DCE-MRI、CT均可有效诊断布病脊柱炎，能够有效显示布病脊柱炎病理特点，但两者联合对布病脊柱炎的效能更高。


关键词: 脊柱炎, 布鲁氏菌, 磁共振成像

Abstract: Objective To diagnose highly suspected brucellosis spondylitis (BS) by dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and computer tomography (CT), and to analyze the diagnostic value of the combination of DCE-MRI and CT in BS. 
Methods A total of 80 patients with highly suspected BS admitted to the First Affiliated Hospital of Hebei North University were selected as the research subjects. All patients underwent pathological examination, CT and DCE-MRI. Taking pathological examination as the gold standard, the diagnostic value of DCE-MRI combined with CT for BS was analyzed. 
Results Among 80 patients with highly suspected BS, 58 cases diagnosed with BS by pathology were selected as BS group, and the remaining 22 patients were selected as non-BS group. Ktrans, Kep and Ve in BS group were higher than those in non-BS group (P＜0.05). The sensitivity and accuracy of DCE-MRI combined with CT in diagnosing BS were higher than those of DCE-MRI and CT alone (P＜0.05). The specificity of CE-MRI combined with CT in diagnosing BS was not statistically significant compared with DCE-MRI and CT alone (P＞0.05). 
Conclusion Both DCE-MRI and CT can be used to effectively diagnose BS, which can effectively display the pathological characteristics of BS. However, the combination of DCE-MRI and CT is more effective for BS.


Key words: spondylitis, brucellosis, magnetic resonance imaging

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