The clinical study on the effect of dexmedetomidine and remifentanil combined anesthesia with laryngeal mask in pediatric department of ophthalmology surgery

doi:10.3969/j.issn.10073205.2016.09.017

Abstract

Abstract: [
Abstract ] Objective Toanalyzethehemodynamiceffectsandclinicalresponseindexof
dexmedetomidineandremifentanilcombinedanesthesiainpediatricdepartmentofophthalmology
surgerywithlaryngealmaskduringperioperativeperiod.Methods The120casesofpatients
comingfromthepediatricophthalmicsurgery wererandomlydividedintothreegroupswith
envelopemethod , asforremifentanilanesthesiagroup , dexmedetomidineanesthesiagroup , the
combinedgroup ( dexmedetomidineandremifentanilcombinedanesthesia
), whichwerefortycases
ineachgroup.Respectivelybeforeinduction ( T 0 ), fiveminutesafterinduction ( T 1 ), laryngeal
maskinsertion ( T 2 ), intrasurgery ( T 3 ), pullouttube ( T 4 ), 5minafterpullouttube ( T 5 ), The
levelsofmeanarterialpressure ( MAP ), respiration ( RR ), heartrate ( HR ) wereseparately
monitored.Beforeinduction ( T 0 ), intrasurgery ( T 3 ) andfiveminutesafterextubation ( T 5 ), the
levelsofcortisolconcentration ( COR ) andnorepinephrine ( NE ) invenousbloodweredetected. Theindexesoflaryngealmaskinsertiontime , theone-timeinsertionoflaryngealcoversuccess
rate , coughchokereactionrate , spontaneousbreathingrecoverytime , removaloflaryngealmask
airwaytime , waketime , emergencedelirium occurrencerate , nausea , vomitingincidencewere
recordedandcomparedamongthreegroupsofpatients.Meanwhile , itwasdonetofurther
comparetheclinicaladversereactionswithinperioperative.Results ThelevelsofMAP , RR , HR ,
CORandNEamongthreegroupsofpatientswerenotstatisticallysignificantatdifferenttime
pointsandatdifferenttimepointsandtheinteractionbetweendifferentgroupsanddifferenttime
pointswasalsonotstatisticallysignificant ( P >0.05 ) .Thespontaneousbreathingrecoverytime
andtheremovaltimeofthelaryngealmaskinthedexmedetomidinegroupwerelessthanthe
remifentanilgroup.butthewaketimeinthedexmedetomidinegroupwaslongerthanthatof
remifentanilgroup ( P <0.05 ) .Thelaryngealmaskinsertiontime , recoverytimeofspontaneous
breathing , theremovaltimeofthelaryngealmaskinthecombinedgroupwereshorterthanthe
remifentanilgroupandthedisposablesuccessrateofthelaryngealmaskinsertionwashigherthan
theremifentanilgroup.theincidenceratesofnauseaandvomitingwerelessthantheremifentanil
group , thelaryngealmaskinsertiontime , theremovaltimeofthelaryngealmaskandwake-up
timewereshorterthanthedexmedetomidinegroup ( P <0.05 ) .Theincidencerateofcough
responseanddeliriumamongthreegroupsshowednosignificantdifference ( P >0.05 ) .Conclusion
Remifentanilanddexmedetomidinecombinedanesthesiacouldhelptostabletheperioperative
hemodynamicparameters , reducesurgicalstressresponseand decreasetherateofadverse
reactionsduringlaryngeal maskinsertionand pulltubetimeforthepatientsofpediatric
ophthalmology with laryngeal mask anesthesia.The clinicaleffectis betterthan that of
remifentanilordexmedetomidinefixedmedicationalone.

Key words: nesthesia, inhalation , ophthalmologicsurgicalprocedures , dexmedetomidine ;remifentanil

WANG Hong1， WANG Yuexin2， ZHAO Jianhui1， SONG Tieying1， GU Kunfeng1. The clinical study on the effect of dexmedetomidine and remifentanil combined anesthesia with laryngeal mask in pediatric department of ophthalmology surgery[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2016.09.017.

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The clinical study on the effect of dexmedetomidine and remifentanil combined anesthesia with laryngeal mask in pediatric department of ophthalmology surgery

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