Abstract: ［Abstract］Objective〖HTSS〗To investigate the distribution of pathogenic bacteria in patients with secondary vaginosis of cervical cancer and to analyze its risk factors.
〖HTH〗〖WTHZ〗Methods〖HTSS〗The clinical data of 120 patients with cervical cancer were analyzed retrospectively. The patients with secondary vaginitis were recorded as the occurrence group, otherwise recorded as the non-occurrence group, the constituent ratio of the factors that may affect the secondary vaginitis of cervical cancer in the two groups were compared, and the possible influencing factors were analyzed by Logistic regression analysis.
〖HTH〗〖WTHZ〗Results〖HTSS〗Among the 120 patients with cervical cancer, 42(35.00%) were secondary vaginosis. A total of 72 strains of pathogenic bacteria were detected in patients with secondary vaginitis. The proportion of fungi, Gram-negative bacteria and Gram-positive bacteria were 52.78%, 31.94% and 15.28%, respectively. Among them, Candida albicans, Escherichia coli and Staphylococcus accounted for the highest proportion, which were 27.78%, 12.50% and 8.33%, respectively. The age >60 years old, past history of vaginitis, diabetes mellitus, postoperative drainage time > 24 hours, chemotherapy and radiotherapy in the occurrence group were higher than those in the non-occurrence group, and the constituent ratio of vaginal lotion was lower than that in the non-occurrence group. The difference was statistically significant(P < 0.05). The results of Logistic regression analysis showed that age >60 years old, past history of vaginosis, diabetes mellitus, postoperative drainage time >24 hours, chemotherapy and radiotherapy were the risk factors of secondary vaginitis of cervical cancer. Vaginal lotion was a protective factor for secondary vaginosis of cervical cancer(P＜0.05).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗The risk of secondary vaginitis of cervical cancer is high. Fungi is the main pathogen and there are many risk factors. It is necessary to formulate prevention and control measures according to the risk factors and encourage patients to use vaginal lotion reasonably.

Key words: Cervical tumor, vaginitis, pathogenic bacteria, risk factors