Abstract: Objective  To observe and analyze the effect and short-term prognosis of chest pain center (CPC) construction on reperfusion therapy for patients with acute ST-segment elevation myocardial infarction (STEMI). 
Methods  A total of 284 patients who were treated with percutaneous coronary intervention (PCI) due to acute chest pain and diagnosed as STEMI before and after CPC construction were selected as the research subjects. According to the time of CPC construction, they were divided into the control group (before CPC construction, n=136) and the observation group (after CPC construction, n=148). The general data, differences in major time points, differences in cardiac function indicators after treatment, and the incidence of cardiac dysfunction during postoperative hospitalization between the two groups were analyzed. 
Results  The observation group had shorter symptom onset to first medical contact (S2FMC), first medical contact to first electrocardiogram (FMC2ECG), door to balloon dilation (D2B), and first medical contact to balloon dilation (FMC2B) as compared with the control group (P＜0.05). The left ventricular ejection fraction (LVEF) after operation in the observation group was higher than that in the control group, while the brain natriuretic peptide (BNP) was lower than that in the control group (P＜0.05). 
Conclusion  CPC construction can effectively shorten the time from onset to reperfusion in STEMI patients, reduce the time of myocardial ischemia, have a significant effect on the recovery of postoperative cardiac function, reduce the occurrence of short-term postoperative cardiac function-related adverse events, and decrease mortality in STEMI patients, showing a relatively higher clinical application value.

Key words: T-segment elevation myocardial infarction, chest pain center, percutaneous coronary intervention