Journal of Hebei Medical University

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Effects of pressurized rapid intravenous infusion of Shenfu on hemodynamics in patients with acute inferior myocardial infarction#br#

  

  1. Department of Cardiology, Yantaishan Hospital of Yantai City, Shandong Province, Yantai 264008, China
  • Online:2018-08-25 Published:2018-07-25

Abstract: [Abstract] Objective〖HTSS〗〓To investigate the effect of rapid intravenous infusion of Shenfu on hemodynamics in patients with acute inferior myocardial infarction.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and twenty  patients with acute inferior wall myocardial infarction who underwent percutaneous coronary intervention were randomly divided into observation group and control group,60 cases in each group. The control group was treated with percutaneous coronary intervention(PCI) Infusion of normal saline, the observation group received treatment of rapid intravenous infusion of Shenfu injection on the basis of the control  group. The hemodynamic parameters, DtoB time, postoperative blood flow classification, adverse reactions, and 30 days of major adverse cardiovascular events were compared between the two groups before and after surgery.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no significant difference in heart rate(HR), left ventricular diastolic pressure(LVEDP), real portfolio project(RPP), maximal rising and falling rate of ventricular pressure(±dP/dtmax) between two groups before operation(P>005). Both HR and ±dP/dtmax at 40 minutes were increased, and LVEDP and RPP were decreased after surgery(P<005). The HR and RPP of the observation group were significantly lower than those of the control group(P<005). The duration of DtoB in the observation group was significantly shorter than that in the control group(P<005). There was no significant difference in TIMI blood flow grade between two groups(P>005). The incidence of adverse events in the observation group and the incidence of MACE in the 30 days after operation were significantly lower than those in the control group(P<005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓In the PCI, rapid intravenous infusion of Shenfu injection can effectively improve the patient′s blood flow, and steadily increase the heart rate and blood pressure, reduce the incidence of nausea and vomiting arrhythmia and the main adverse cardiovascular events, with safety , which is worthy of promotion.

Key words: inferior wall myocardial infarction, percutaneous coronary intervention, Shenfu injection