Abstract: [ Abstract ] Objective Tostudythecorrelationofneutrophil-lymphocyteratio ( NLR ) andthe
leftventricularsystolicfunctioninpatientswithacutecoronarysyndrome ( ACS ) .Methods A
totalof438 cases with ACS wereincludedinthestudy.The NLR was obtained before
endovascularreperfusiontherapyandmedicationtreatment.Allofthepatientswereexaminedby
echocardiographywithin72 hoursafteradmissionandobtainedtheleftventricularejection
fraction ( LVEF ) .Thestudypopulationwasincludedintoleftventricularsystolicfunctiongroup
(
LVEF<50% ) andnon-leftventricularsystolicfunction ( LVEF≥50% ) .Results ①Compared
withnon-leftventricularsystolicfunctiongroup , theage , hsCRP , WBCcountandNLRlevels wereobviouslyhigherinthepatientswithleftventricularsystolicfunction , thedifferencewas
statisticallysignificant ( P <0.05 ) .AMIprevalencewashigherandtheratioofreperfusionwas
lowinleftventricularsystolicfunctiongroupthanthatinnon-leftventricularsystolicfunction
group ( P <0.05 ) .② Pearsoncorrelationanalysisshowedthat NLR and LVEF valuehad
significantnegativecorrelationinpatientswithACS ( r =-0. 582 , P <0.01 ) .③Themultivariate
LogisticregressionanalysisshowedthatNLRwasanindependentriskfactorforthedevelopment
ofleftventricularsystolicfunctioninpatientswithACSafteradjustedforage , thehsCRP , AMI
andPCI / CABG reperfusiontherapy ( OR =1.398 , 95% CI =1.151-1.696 , P =0.001 ) .
Conclusion NLRandLVEFwassignificantlynegativecorrelationinpatientswithACS.NLR
canbeusedasindepen

Key words: acutecoronarysyndrome , strokevolume , ventriculardysfunction, left