Abstract: Objective Optical coherence tomography (OCT)was used to quantitatively measure of peripapillary retinal nerve fiber layer (RNFL)thickness and the change of macular retinal thickness,understanding of correlation between the variation characteristics of patients′RNFL thickness and macular retinal thickness and visual outcome following Phacoemulsification (Phaco)of cataract patients.Methods Forty nine patients (70 eyes)diagnosed with age-related cataract,in Xuanwu Hospital,Capital Medical University,were divided into two groups,patients with diabetes in the diabetes group,20 cases (32 eyes),not with diabetes in normal group,29 cases (38 eyes),the cataract combined with phaco intraocular lens implantation operation was successfully implemented,the peripapillary RNFL thickness and macular retinal thickness changes were analyzed by means of OCT after Phaco operation at different time points (including 3 days,2 weeks,1 month,3 months,6 months after operation),to discuss correlation between the above indexes and postoperative best corrected visual acuity(CVA).Results In normal group,the peripapillary RNFL thickness showed statisticly negative correlation with CVA at the time 2 weeks,1 month,3 months after operation(r-0.466,-0.490,-0.511,P<0.01);In normal group,the macular thickness showed statisticly negative correlation with CVA at the time 2 weeks,1 month after operation(r=-0.309,-0.315,P<0.05)respectively.In diabetic group,the peripapillary RNFL thickness showed statisticly negative correlation with CVA in 2 weeks to 6 months following surgery(r=-0.365,-0.447,-0.512,-0.499,P<0.01);In diabetic group,the macular thickness showed statisticly negative correlation with CVA in 3 days to 6 months following surgery(r=-0.427,-0.490,-0.653,-0.451,-0.353,P<0.01).Conclusion The macular retinal thickness in Phaco patients after cataract is the main reason that affects the vision,at the same time cataract after Phaco peripapillary RNFL thickness has impact on visual acuity at different time and different degrees.

Key words: cataract, optic nerve, phacoemulsification