Abstract: Objective To systematically evaluate the safety and feasibility of fast track surgery in perioperative period of hepatectomy.Methods Literatures of PubMed,Embase, ScinceDirect,Google Scholar,WanFang and CNKI published before March 2014 were searched. The methodological quality including RCTs and CCTs were assessed.Results Seven RCTs and two CCTs involving 1 072 patients met the inclusion criteria.Compared with those by conventional way the patients managed by fast track surgery had less complications (RR=-0.01,95%CI=-0.06 to -0.03,P=0.58),faster bowel function recovery (MD=-0.90,95%CI=-1.28 to -0.52,P<0.01)and shorter postoperative hospital stay (MD=-2.45,95%CI=-3.99 to -0.91,P<0.01),but not statistically increased severe complications (bile leak,pleural effusion,intraperitoneal abscess)(RR=0.93,95%CI=0.60 to 1.45,P=0.75).Conclusion Fast track surgery is safe and feasible in perioperative period of hepatectomy.

Key words: hepatectomy, rehabilitation, Meta-analysis