Abstract: Objective To explore the effect and safety of laparoscopic surgery on children with congenital choledochus dilatation(CCD). 
Methods A total of 50 children with CCD who underwent laparoscopic surgery were selected as the research subjects(the observation group), and 50 children with CCD who underwent laparotomy during the same period were selected as the control group. Both groups underwent the resection of bile duct cysts and Roux-Y anastomosis of common hepatic duct-jejunum. The operation-reelated conditions of two groups were compared, and the liver function indexes and inflammation indexes of the two groups were detected before and after operation. 
Results The duration of operation was longer in the observation group than in the control group, the intraoperative bleeding volume was lower than that of the control group, and the postoperative defecation time, postoperative time of food intake and postoperative hospital stay were shorter than those of the control group(P＜0.05). There were significant differences in the level of total bilirubin(TBIL), alanine aminotransferase(ALT), aspartate transaminase(AST), C-reactive protein(CRP) and interleukin 6(IL-6) in the observation group and the control group from 1 d before operation to 7 d after operation, and the incidence of complications was lower in the observation group than in the control group, suggesting significant difference(χ2=5.316，P＜0.05). There was no significant difference in the average operation and hospitalization expenses between two groups(t=1.518, P＞0.05). 
Conclusion Compared with the laparotomy, the laparoscopic resection of bile duct cysts combined with Roux-Y anastomosis of common hepatic duct-jejunum can effectively reduce the traumatic stress and inflammatory response, with faster postoperative recovery and fewer complications.

Key words: choledochal cyst, laparoscopy, choledochostomy