Abstract: ABSTRACT:Objective To compare the diagnostic value of shear wave elastography and single-photon emission computed tomography (SPECT)99m TcO4 - imaging in thyroid cancer. Methods All 148 thyroid nodules as research subjects were checked by shear wave elastography and radionuclide SPECT imaging,based by the pathology as the gold standard,two methods for calculating the diagnosis of thyroid cancer sensitivity,specificity,accuracy,positive predictive value and negative predictive value were compared.Results All of the 148 thyroid nodules,there were 39 malignant nodules (26.35%),109 benign nodules (73.65%).About the sensitivity, specificity,accuracy,positive predictive value and negative predictive value,shear wave elastography in the diagnosis of thyroid cancer in a variety of indicators were higher than SPECT 99m TcO4 - imaging.Conclusion Shear wave elastography in the diagnosis of thyroid cancer is higher than radionuclide SPECT 99m TcO4 - imaging,and shear wave elastography should be preferred for first clinical use.The combination of the two methods will increase the value in the diagnosis of thyroid carcinoma.

Key words: thyroid neoplasms, diagnostic imaging, comparative study