河北医科大学学报

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超声影像学评价对促排卵后妊娠结局的预测作用

  

  1. 1.河北省平乡县人民医院功能科,河北 平乡 054500;2.河北医科大学第二医院生殖医学科,河北 石家庄 050000
  • 出版日期:2019-03-25 发布日期:2019-03-20
  • 作者简介:张志峰(1973-),女,河北平乡人,河北省平乡县人民医院副主任医师,医学学士,从事超声医学诊断研究。

Predictive effect of ultrasound imaging evaluation on pregnancy outcome after ovulation induction#br#

  1. 1.Department of Function, Pingxiang General Hospital, Hebei Province, Pingxiang
    054500, China; 2.Department of Reproductive Medicine, the Second Hospital of
    Hebei Medical University, Shijiazhuang 050000, China
  • Online:2019-03-25 Published:2019-03-20

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗通过超声观察接受控制性促排卵方案(control ovarian stimulation,COS)助孕患者子宫内膜容受性及卵巢内卵泡储备影像学特点,分析超声评估对不孕患者妊娠结局的预测作用。
〖HTH〗方法〖HTSS〗〖KG*2〗回顾性分析接受COS治疗的不孕症患者209周期的相关资料。根据妊娠结局分为妊娠组(30周期)和未妊娠组(未妊娠者中随机选取30周期),比较2组子宫内膜厚度、子宫内膜类型、子宫内膜容积、卵巢体积、窦卵泡数以及排卵前最大卵泡直径。根据内膜厚度分为<8 mm、8~14 mm、>14 mm组,根据内膜类型分为A型、B型、C型组,根据内膜容积分为<2 mL、2~4 mL、>4 mL,根据卵巢体积分为<3 cm3、3~6 cm3、>6 cm3,根据窦卵泡数分为<5个、5~15个、>15个,比较各组妊娠率。
〖HTH〗结果〖HTSS〗〖KG*2〗妊娠组子宫内膜厚度和内膜容积均大于未妊娠组,妊娠组子宫内膜形态A型较多,未妊娠组子宫内膜形态C型较多,妊娠组卵巢体积、窦卵泡数明显大于或多于未妊娠组,差异有统计学意义(P<005); 2组人绒毛膜促性腺激素日最大卵泡直径差异无统计学意义(P>005)。子宫内膜厚度8~14 mm组妊娠率明显高于<8 mm、>14 mm组,子宫内膜A型组妊娠率明显高于B型、C型组,子宫内膜容积>4 mL组妊娠率明显高于<2 mL、2~4 mL组,卵巢体积3~6 cm3组妊娠率明显高于<3 cm3、>6 cm3组,卵泡数5~15个组妊娠率明显高于<5个、>15个组,差异均有统计学意义(P<005)。
〖HTH〗结论〖HTSS〗〖KG*2〗对于接受COS治疗的不孕患者,超声监测子宫内膜厚度8~14 mm、子宫内膜容积>4 mL、子宫内膜类型A型、卵巢体积3~6 cm3、窦卵泡数5~15个时妊娠的概率更大。

关键词: 不育, 女(雌)性, 妊娠结局, 排卵诱导, 超声检查

Abstract: [Abstract]〓Objective〖HTSS〗〓To analyze the predictive effect of ultrasonography on pregnancy outcomes of infertile women by observing the intraovarian follicle reserve imaging characteristics and endometrial receptivity of infertile women receiving controlled ovarian stimulation(COS) via ultrasonography.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Retrospective  analysis the related data of 209 cycles were taken from infertile patients treated with COS. According to the pregnancy outcome, the cycles were divided into the pregnancy group(30 cycles) and the nonpregnant group(30 cycles randomly selected from the nonpregnant patients). The endometrial thickness, endometrial type, endometrial volume, ovarian volume, number of antral follicles and the maximum diameter of follicles before ovulation of both groups were compared. The 60 cycles were divided into group<8 mm, group 8-14 mm, and group>14 mm, according to the endometrial thickness; type A, type B, and type C, according to the endometrial type; group<2 mL group 2-4 mL and group>4 mL, according to the endometrial volume; group<3 cm3, group 3-6 cm3, and group>6 cm3 ,according to the ovarian volume; group<5, group 6-15 and group >15, according to the number of antral follicles. The pregnancy rates of each group were compared.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The endometrial thickness and endometrial volume of the pregnant group were higher than those of the nonpregnant group. In the pregnant group,the endometrial morphology type A was in the majority, while in the nonpregnant group, the endometrial morphology type C was in the majority; the ovarian volume and the number of antral follicles in the pregnant group were significantly higher than those of the nonpregnant group, the differences above were statistically significant(P<005). There was no significant difference in the maximum follicle diameter on the day of human chorionic gonadotropin injection between the two groups(P>005). The pregnancy rate of the endometrial thickness 8-14 mm group was significantly higher than that of the group<8 mm and group>14 mm; the pregnancy rate of endometrial type A group was significantly higher than that of type B and type C; the pregnancy rate of endometrial volume>4 mL group was significantly higher than that of group <2 mL and group 2-4 mL; the pregnancy rate of ovarian volume 3-6 cm3 group was significantly higher than that of group<3 cm3 and group >6 cm3 , and the pregnancy rate of 5-15 follicles group was significantly higher than that of group<5 and group>15, the differences above were statistically significant(P<005). 
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓For infertility patients receiving COS treatment,the ones with endometrial thickness between 8-14 mm, endometrial volume greater than 4 ml, endometrium type A, ovaria volume between 3-6 cm3 and  the number of antral follicles between 5-15 are more likely to get pregnant.

Key words: infertility, female, pregnancy outcome, ovulation induction, ultrasonography