河北医科大学学报

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良性阵发性位置性眩晕与骨密度的研究#br#

  

  1. 1.河北省石家庄市第三医院耳鼻喉科，河北 石家庄 050011； 2.河北省石家庄市第三医院放射科，河北 石家庄 050011
  • 出版日期:2020-09-25 发布日期:2020-09-27
  • 作者简介:李云（1982-），女，河北石家庄人，河北省石家庄市第三医院主治医师，医学硕士，从事耳鼻咽喉科疾病诊治研究。
  • 基金资助:
    河北省医学科学研究重点课题计划（20181039）

Study on benign paroxysmal plsitional vertigo and bone mineral density#br#

  1. 1.Department of Otorhinolaryngology, the Third Hospital of Shijiazhuang, Hebei Province, Shijiazhuang
    050011, China; 2.Department of Radiological, the Third Hospital of Shijiazhuang,
    Hebei Province, Shijiazhuang 050011, China
  • Online:2020-09-25 Published:2020-09-27

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摘要： 目的  〖KG*2〗探讨良性阵发性位置性眩晕（benign paroxysmal positional vertigo,BPPV）患者骨密度的变化规律及骨密度对BPPV的影响。
〖HTH〗方法  〖KG*2〗选取BPPV患者105例为试验组，健康体检者108例为对照组。2组均常规行耳鼻喉科专科检查、眼震视图仪检查、位置试验、全身骨密度测定（双能X线吸收法，采用T-值评分计算），分析不同性别、不同年龄BPPV患者全身骨密度Ｔ值的变化规律。分析骨密度对BPPV的影响。
〖HTH〗结果  〖KG*2〗试验组骨密度T值低于对照组，差异有统计学意义（P＜0.05）。男性和女性试验组骨密度T值均低于对照组，骨密度降低发生率高于对照组；2组女性骨密度T值均低于男性，女性骨密度降低发生率高于男性，差异有统计学意义（P＜0.01）。41～50岁、51～60岁、61～70岁和≥71岁试验组骨密度T值低于对照组，骨密度降低发生率高于对照组，差异有统计学意义（P＜0.05或P＜0.01），≤40岁试验组和对照组骨密度T值和骨密度降低发生率差异无统计学意义（P＞0.05）。随年龄增加，2组骨密度T值呈降低趋势，骨密度降低发生率呈升高趋势，差异有统计学意义（P＜0.05）。Logistic回归分析结果显示，骨密度降低是BPPV的危险因素。
〖HTH〗结论  〖KG*2〗BPPV患者骨密度T值明显低于正常对照组，女性尤其明显，并且随年龄增加呈降低趋势。骨密度降低是BPPV的危险因素。

关键词: 眩晕, 骨密度, 危险因素

Abstract: Objective  To explore the change rules of bone mineral density in patients with benign paroxysmal positional vertigo(BPPV) and the effect of bone mineral density on BPPV.
  Methods  The 105 BPPV patients were selected as the experimental group, and 108 healthy subjects were selected as the control group. Both group are taken ENT specialist examination, nystagmus inspection, position test, and whole body bone density determination(dual energy X-ray absorption method, calculated by T-score). Then we concluded the change rules of the whole body bone mineral density T-value of BPPV patients in different genders and ages, and the effect of bone density on BPPV.
  Results  The T-value of bone mineral density in the experimental group was lower than that in the control group, and the difference was statistically significant(P＜0.05).The bone mineral density T value of the male and female test groups was lower than that of the control group, and the incidence of bone density reduction was higher than that of the control group.The bone mineral density T-value of the two groups of women was lower than that of men, and the incidence of bone density reduction in women was higher than that of men, the difference was statistically significant(P＜0.01).The bone mineral density T-value of the test group between 41 to 50 years old, 51 to 60 years old, 61 to 70 years old, and 71 years or older was lower than that of the control group, and the incidence of bone density reduction was higher than that of the control group. The difference was statistically significant(P＜0.05 or P＜0.01). There was no statistically significant difference in bone mineral density T-value and the incidence of bone mineral density reduction between the test group and the control group younger than or equal to 40 years old(P＞0.05). With the increase of age, the bone density T value of the two groups showed a decreasing trend, and the incidence of bone density decrease showed an increasing trend, and the difference was statistically significant(P＜0.05). Logistic regression analysis showed that bone density reduction was a risk factor for BPPV.
  Conclusion  The T-value of bone mineral density in BPPV patients is significantly lower than that in the normal control group, and showes an increasing trend with age, especially in women. Decreased bone density is a risk factor for BPPV.

Key words: vertigo, bone density, risk factors

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