关键词: 缺血脑卒中, 肌减少症, 预后

Abstract: Objective To explore the effect of early sarcopenia screening on the prognosis and rehabilitation of patients with ischemic stroke. 
Methods A total of 200 patients with ischemic stroke admitted to Hebei Petro China Central Hospital were selected and divided into stroke with sarcopenia group (n=100) and stroke group (n=100) according to presence of accompanied sarcopenia. Skeletal muscle mass/height, calf circumference,body mass index (BMI) and prognostic outcome at 6 months after stroke were compared between two groups. The patients were divided into good prognosis group (n=128) and poor prognosis group (n=72) according to the rehabilitation effect. The influencing factors of the rehabilitation effect of patients were analyzed by Logistic data model. 
Results The skeletal muscle mass/height, calf circumference and BMI of the stroke with myopenia group were lower than those of the stroke group (P＜0.05), and the poor prognosis rate of the stroke with myopenia group was higher than that of the stroke group (P＜0.05). The National Institute of Health Stroke Scale （NIHSS） score, Glasgow Coma Scale （GCS） score, mean arterial pressure variability, hypertension, diabetes, and atrial fibrillation at admission of the good prognosis group were compared with those of the poor prognosis group (P＜0.05), Multivariate Logistic analysis showed that the higher the NIHSS score at admission, the lower the GCS score at admission, the greater the variability of mean arterial pressure, and the presence of atrial fibrillation and sarcopenia were independent risk factors for poor prognosis in ischemic stroke patients (P＜0.05). 
Conclusion Sarcopenia in patients with ischemic stroke is unfavorable for prognosis and recovery of patients. Early screening of ischemic stroke patients with sarcopenia has certain clinical value. 

Key words: ischemic stroke, sarcopenia, prognosis