等离子电切与激光汽化治疗良性前列腺增生临床效果及对IPSS、QOL、Qmax、PVR的影响

doi:10.3969/j.issn.10073205.2019.02.012

河北医科大学学报

等离子电切与激光汽化治疗良性前列腺增生临床效果及对IPSS、QOL、Qmax、PVR的影响

1.冀中能源峰峰集团总医院泌尿外科，河北邯郸 056200；2.冀中能源峰峰集团总医院骨科，河北邯郸 056200；
3.冀中能源峰峰集团总医院呼吸内科，河北邯郸 056200

出版日期:2019-02-25 发布日期:2019-01-16
作者简介:王竞（1981-），男，辽宁抚顺人，冀中能源峰峰集团总医院主治医师，医学学士，从事泌尿外科疾病诊治研究。
基金资助:
河北省重点研发计划（172777217）

Clinical efficacy of plasma electroresection and laser vaporization in the treatment of benign prostatic hyperplasia and their influence on IPSS, QOL, Qmax and PVR

1.Department of Urology Surgery, the General Hospital of Jizhong Energy Fengfeng Group, Handan
056200, China; 2.Department of Orthopedics, the General Hospital of Jizhong Energy Fengfeng
Group, Handan 056200, China; 3.Department of Respiratory Medicine, the General
Hospital of Jizhong Energy Fengfeng Group, Handan 056200, China

Online:2019-02-25 Published:2019-01-16

摘要/Abstract

摘要： ［摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗观察等离子电切与激光汽化治疗良性前列腺增生临床效果及对国际前列腺症状评分(International Prostate Symptom Score, IPSS)、生活质量评分(Quality of Life,QOL)、最大尿流率(Qmax)、残余尿量(postvoiding residual volume,PVR)的影响。
〖HTH〗方法〖HTSS〗〖KG*2〗回顾性分析前列腺增生且行手术切除的患者78例，其中43例接受经尿道等离子双极电切治疗的患者为电切组，35例接受1 470 nm半导体激光汽化治疗的患者为激光组。比较2组临床疗效、术中血红蛋白（hemoglobin，Hb）下降值、血钠下降值、膀胱冲洗时间、手术时间、留置导管时间、住院时间，治疗前后IPSS、QOL、Qmax、PVR，术中术后出血、继发性出血、电切综合征等并发症发生情况。
〖HTH〗结果〖HTSS〗〖KG*2〗2组临床疗效及治疗总有效率差异无统计学意义(P＞005)。激光组术中Hb下降值、术中血钠下降值明显小于电切组，膀胱冲洗时间、留置导管时间、住院时间明显短于电切组，手术时间明显长于电切组(P＜005)。治疗前，2组IPSS、QOL、Qmax、PVR差异均无统计学意义(P＞005)；治疗后，2组IPSS、QOL、PVR明显低于治疗前，Qmax明显高于治疗前，差异均有统计学意义(P＜005)，但2组IPSS、QOL、Qmax、PVR差异无统计学意义(P＞005)。2组不良反应发生率差异无统计学意义(P＞005)。
〖HTH〗结论〖HTSS〗〖KG*2〗1 470 nm半导体激光汽化治疗与经尿道等离子双极电切治疗良性前列腺增生临床效果均显著，均能有效改善患者IPSS、QOL、Qmax、PVR；经尿道等离子双极电切治疗手术时间更短，1 470 nm半导体激光汽化治疗出血更少。

关键词: 前列腺增生, 经尿道前列腺切除术, 激光, 半导体

Abstract: ［Abstract］〓Objective〖HTSS〗〓To investigate the clinical efficacy of plasma electroresection and laser vaporization in the treatment of benign prostatic hyperplasia and their influence on international prostate symptom score(IPSS),quality of life(QOL),maximum urine flow rate(Qmax) and postvoid residual volume(PVR).
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 78 patients with benign prostatic hyperplasia who underwent surgical resection were analyzed retrospectively. Among them, 43 patients treated with transurethral plasmakinetic bipolar resection were labeled as electroresection group and 35 patients treated with 1 470 nm semiconductor laser vaporization were labeled as laser groups. The clinical efficacy, intraoperative hemoglobin(HB) falling value, blood sodium falling value, bladder irrigation time, operation time, indwelling catheter time and hospitalization time of the two groups were compared.IPSS, QOL, Qmax and PVR before and after treatment and complications such as intraoperative and postoperative bleeding, secondary bleedingand transurethral resection syndrome were compared.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no statistically significant difference in clinical efficacy and total effective rate between two groups(P＞005). The HB falling value and blood sodium falling value in laser group were significantly lower than those in electroresection group, bladder irrigation time, indwelling catheter time and hospitalization time were significantly shorter than those in electroresection group, and the operation time was significantly longer than that in electroresection group(P＜005). Before treatment, there was no significant difference in IPSS, QOL, Qmax and PVR between two groups(P＞005). After treatment, IPSS, QOL, PVR in the two groups were significantly lower than that before treatment. Qmax was significantly higher than that before treatment, and the difference was statistically significant(P＜005). However, there was no significant difference in IPSS, QOL, Qmax and PVR between two groups(P＞005). There was no significant difference in the incidence of adverse reactions between two groups(P＞005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Both 1 470 nm semiconductor laser vaporization treatment and transurethral plasmakinetic bipolar resection treatment have significant clinical effects in the treatment of benign prostatic hyperplasia, they can effectively improve the patient′s IPSS, QOL, Qmax and PVR, transurethral plasmakinetic bipolar resection treatment is with shorter operation time, 1 470 nm semiconductor laser vaporization treatment is with less bleeding.

Key words: prostatic hyperplasia, transurethral resection of prostate, lasers, semiconductor

王〓竞1，时少显1，和学强1，李海涛1，段晓亮2，孙〓波3. 等离子电切与激光汽化治疗良性前列腺增生临床效果及对IPSS、QOL、Qmax、PVR的影响[J]. 河北医科大学学报, doi: 10.3969/j.issn.10073205.2019.02.012.

WANG Jing1, SHI Shaoxian1, HE Xueqiang1, LI Haitao1, DUAN Xiaoliang2, SUN Bo3. Clinical efficacy of plasma electroresection and laser vaporization in the treatment of benign prostatic hyperplasia and their influence on IPSS, QOL, Qmax and PVR[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2019.02.012.

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等离子电切与激光汽化治疗良性前列腺增生临床效果及对IPSS、QOL、Qmax、PVR的影响

Clinical efficacy of plasma electroresection and laser vaporization in the treatment of benign prostatic hyperplasia and their influence on IPSS, QOL, Qmax and PVR

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