河北医科大学学报

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不同类型急性冠状动脉综合征患者心率变异性的差异研究

  

  1. 1.河北省保定市第一中心医院心内三科,河北 保定 071000;2.河北省保定裕东医院心电图室,河北 保定 071000;
    3.河北省保定市第一中心医院心内二科,河北 保定 071000;4.河北省保定市第一中心医院心内四科,
    河北 保定 071000;5.中国人民解放军陆军第82集团军医院泌尿外科,河北 保定 071000
  • 出版日期:2019-05-25 发布日期:2019-05-22
  • 作者简介:刘伟(1982-),男,河北保定人,河北省保定市第一中心医院主治医师,医学硕士,从事心血管内科疾病诊治研究。

Study on the difference of heart rate variability in patients with different types of acute coronary syndrome

  1. 1.The Third Department of Cardiovascular Medicine, the First Central Hospital of Baoding, Hebei
    Province, Baoding 071000,China; 2.Department of Electrocardiogram, Baoding Yudong Hospital,
    Hebei Province,Baoding 071000,China; 3.The Second Department of Cardiovascular Medicine,
    the First Central Hospital of Baoding,Hebei Province, Baoding 071000, China; 4.The Fourth
    Department of Cardiovascular Medicine, the First Central Hospital of Baoding, Hebei Province,
    Baoding 071000, China; 5.Department of Urology,  the 82nd Group Military Hospital of
    the Chinese People′s Liberation Army, Hebei Province, Baoding 071000, China
  • Online:2019-05-25 Published:2019-05-22

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨急性冠状动脉综合征中急性心肌梗死与不稳定型心绞痛心率变异性,明确自主神经变化规律,为进一步观察治疗及指导预后提供参考价值和新的治疗策略。
〖HTH〗方法〖HTSS〗〖KG*2〗将急性冠状动脉综合征患者根据临床分型分为急性心肌梗死组(A组,32例)和不稳定型心绞痛组(B组,47例),24 h动态心电图检查分析其心率变异性。
〖HTH〗结果〖HTSS〗〖KG*2〗A组心电图RR间期的标准差(standard deviations of normaltonormal RR intervals,SDNN)、心电图RR间期均值的标准差(standard deviation of the average normaltonormal intervals,SDANN)及心电图相邻RR间期差值的均方根(root mean square of successive differece,RMSSD)均明显小于B组,差异有统计学意义(P<005),2组相差在50 ms的RR间期的数量占所有RR间期数量的比例(proportion of number of pairs of adjacent normaltonormal intervals by more than 50 ms,pNN50)差异无统计学意义(P>005)。
〖HTH〗结论〖HTSS〗〖KG*2〗急性冠状动脉综合征中急性心肌梗死组较不稳定型心绞痛组自主神经功能受损更严重,应根据心率变异性变化情况积极改善患者自主神经功能状态,降低冠心病并发症发生率,改善冠心病患者预后。

关键词: 急性冠状动脉综合征, 心率变异性, 心电描记术

Abstract: [Abstract]〓Objective〖HTSS〗〓To investigate the heart rate variability of acute myocardial infarction and unstable angina in acute coronary syndrome, and to clarify the autonomic nerve change rule, so as to provide reference value and new treatment strategy for further observation and treatment and guidance of prognosis.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Patients with acute coronary syndrome were divided into acute myocardial infarction group(group A, 32 cases) and unstable angina pectoris group(group B, 47 cases) according to clinical classification.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Standard deviations of normaltonormal RR intervals(SDNN), standard deviation of the average normaltonormal intervals(SDANN) and root mean square of successive differece(RMSSD) of group A were significantly lower than that of group B, with statistically significant difference(P<005), while proportion of number of pairs of adjacent normaltonormal intervals by more than 50 ms(pNN50) of 2 groups showed no statistically significant difference(P>005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓In acute coronary syndrome, the autonomic nervous function of the acute myocardial infarction group is more seriously impaired than that of the unstable angina group. The autonomic nervous function of the patients should be actively improved according to the changes in heart rate variability, so as to reduce the incidence of coronary heart disease complications and improve the prognosis of patients with coronary heart disease.

Key words: acute coronary syndrome, heart rate variability, electrocardiography