河北医科大学学报

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腹腔镜胰十二指肠切除术患者术后肺部并发症影响因素探讨

  

  1. 河北医科大学第二医院麻醉科,河北 石家庄 050000
  • 出版日期:2019-03-25 发布日期:2019-03-20
  • 作者简介:杨晓荣(1990-),女,河北邯郸人,河北医科大学第二医院医师,医学硕士,从事临床麻醉学研究。
  • 基金资助:
    河北医科大学第二医院科学研究基金项目(zh2017045)

Risk factors for postoperative pulmonary complications in patients undergoing laparoscopic pancreaticoduodenectomy

  1. Department of Anesthesiology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2019-03-25 Published:2019-03-20

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗探讨腹腔镜胰十二指肠切除术(laparoscopic pancreaticoduodenectomy,LPD)患者术后肺部并发症(postoperative pulmonary complications,PPCs)的高危因素,以进一步优化LPD围术期麻醉管理,降低PPCs发生率。
〖HTH〗方法〖HTSS〗〖KG*2〗回顾性分析100例择期LPD患者的临床资料,记录患者性别、年龄、体重指数、美国麻醉医师协会分级、吸烟史、慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)、高血压、糖尿病、冠心病、肝功能分级、吸入氧浓度(fraction of inspiration O2,FiO2)、术中输血、术中输液量、术中保温、术中应用乌司他丁、术后镇痛、ICU留观、手术时间、术后住院时间,分析LPD患者术后发生PPCs的危险因素。
〖HTH〗结果〖HTSS〗〖KG*2〗100例LPD患者术后发生PPCs 33例,发生率为33.0%。PPCs组吸烟率、COPD发生率、留观ICU比例及FiO2(纯氧)使用率高于非PPCs组,乌司他丁使用率低于非PPCs组,年龄大于非PPCs组,住院时间长于非PPCs组,差异均有统计学意义(P<005)。多因素Logistic回归分析结果显示,有吸烟史、合并COPD、100% FiO2为LPD患者术后发生PPCs的高危因素。
〖HTH〗结论〖HTSS〗〖KG*2〗术前有吸烟史、合并COPD、术中麻醉期间100% FiO2为LPD患者发生PPCs的高危因素。

关键词: 胰十二指肠切除术, 腹腔镜, 手术后并发症, 危险因素

Abstract: [Abstract]〓Objective〖HTSS〗〓To identify the risk factors of postoperative pulmonary complications in patients undergoing laparoscopic pancreaticoduodenectomy(LPD) and further improve perioperative anesthesia management and reduce the incidence of postoperative pulmonary complications(PPCs).
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A retrospective survey was undertaken on 100 patients underwent LPD operation. A total of 19 items of information such as gender, age, BMI, ASA classification, smoking, chronic obstructive pulmonary disease(COPD), hypertension, diabetes, coronary heart disease, liver functional grading, fraction of inspiration O2(FiO2), blood transfusion, intraoperative fluid volume, intraoperative warming, application of ulinastatin during operation, postoperative analgesia, ICU observation, operation time, postoperative hospitalization time were collected, and the risk factors for PPCs were analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Postoperative pulmonary complications occurred in 33 of the 100 patients, and the incidence was 33.0%. The rate of smoking, COPD, ICU observation, pure oxygen inhalation in PPCs group was higher than that in NPPCs group, ulinastatin application was lower in PPCs group, age was older and hospitalization time was longer in PPCs group, and the difference was statistically significant(P<005). The multivariate logistic regression analysis displayed that smoking, COPD, pure oxygen inhalation were the risk factors of postoperative pulmonary complications in patients undergoing LPD.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The preoperative history of smoking and COPD, pure oxygen inhalation in perioperative period were high risk factors of postoperative pulmonary complications in patients undergoing LPD.

Key words: pancreaticoduodenectomy, laparoscopes, postoperative complications, risk factors