卡前列素氨丁三醇在产后出血者中的临床效果及对FIB、DD水平的影响

doi:10.3969/j.issn.10073205.2019.07.015

河北医科大学学报

卡前列素氨丁三醇在产后出血者中的临床效果及对FIB、DD水平的影响

湖北省鄂州市中心医院妇产科，湖北鄂州 436000

出版日期:2019-07-25 发布日期:2019-07-16
作者简介:熊英（1980-），女，湖北鄂州人，湖北省鄂州市中心医院主治医师，医学学士，从事妇产科疾病诊治研究。

Clinical effect of carprostol tromethamine in patients with postpartum hemorrhage and its effect on FIB and DD#br#

Department of Obstetrics and Gynecology, Ezhou Central Hospital, Hubei Province，Ezhou 436000， China

Online:2019-07-25 Published:2019-07-16

摘要/Abstract

摘要： ［摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗观察卡前列素氨丁三醇在产后出血者中的临床效果及对纤维蛋白原(fibrinogen，FIB)、D二聚体(DDimer，DD)水平的影响。
〖HTH〗方法〖HTSS〗〖KG*2〗选取产后出血者78例，应用抽签法将其随机分为研究组和对照组，每组39例。对照组采用缩宫素治疗，研究组采用卡前列素氨丁三醇治疗。比较2组的治疗效果、FIB和DD水平、产后出血量、恶露持续时间、子宫底下降速度、子宫收缩时间。
〖HTH〗结果〖HTSS〗〖KG*2〗研究组治疗效果优于对照组（P＞005）。治疗后，2组FIB、DD水平低于治疗前，研究组FIB、DD水平低于对照组（P＜005）。研究组产后1 h、12 h出血量少于对照组，子宫收缩时间长于对照组，子宫底下降速度快于对照组，恶露持续时间短于对照组（P＜005）。
〖HTH〗结论〖HTSS〗〖KG*2〗卡前列素氨丁三醇治疗产后出血，可改善出血者临床症状，降低其FIB、DD水平，提高其生活质量，具有较高的安全性，值得在临床推广应用。

关键词: 产后出血, 卡前列素氨丁三醇, 纤维蛋白原, D二聚体

Abstract: ［Abstract］〓Objective〖HTSS〗〓To investigate the clinical effects of carprostol tromethamine in patients with postpartum hemorrhage and the effects on fibrinogen(FIB) and Ddimer(DD) levels.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 78 patients with postpartum hemorrhage were enrolled. The patients were randomly divided into study group and control group by weighting method, with 39 cases in each group. The control group was treated with oxytocin, and the study group was treated with carprost tromethamine. The therapeutic effects, FIB and DD levels, postpartum hemorrhage, duration of lochia, rate of decline of the uterus, and uterine contraction time were compared between the two groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The therapeutic effect of the study group is better than that of the control group(P＜005). After treatment, the levels of FIB and DD in the two groups were lower than those before treatment, and the levels of FIB and DD in the study group were lower than those in the control group(P＜005). The bleeding volume of the study group at 1 h and 12 h after birth was less than that of the control group. The uterine contraction time was longer than that of the control group. The uterus bottom decreased faster than the control group, and the duration of lochia was shorter than that of the control group(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Carbaryl tromethamine is effective in the treatment of postpartum hemorrhage, which improves clinical symptoms, reduces the level of FIB and DD, improves the quality of life, and has higher safety, which can be widely applied in clinical practice.

Key words: postpartum hemorrhage, carprostol tromethamine, fibrinogen, Ddimer

熊〓英，马宏莲，罗红霞*. 卡前列素氨丁三醇在产后出血者中的临床效果及对FIB、DD水平的影响[J]. 河北医科大学学报, doi: 10.3969/j.issn.10073205.2019.07.015.

XIONG Ying, MA Honglian， LUO Hongxia*. Clinical effect of carprostol tromethamine in patients with postpartum hemorrhage and its effect on FIB and DD#br#[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2019.07.015.

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卡前列素氨丁三醇在产后出血者中的临床效果及对FIB、DD水平的影响

Clinical effect of carprostol tromethamine in patients with postpartum hemorrhage and its effect on FIB and DD#br#

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