河北医科大学学报 ›› 2024, Vol. 45 ›› Issue (6): 627-631.doi: 10.3969/j.issn.1007-3205.2024.06.002

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动脉瘤性蛛网膜下腔出血并发脑水肿的影响因素及预后分析

  

  1. 四川大学华西医院神经疾病综合病房,四川 成都 610000

  • 出版日期:2024-06-25 发布日期:2024-06-25
  • 作者简介:何茜(1987-),女,四川成都人,四川大学华西医院护师,医学学士,从事神经疾病护理研究。
  • 基金资助:
    四川省科技计划项目(2020YJ0033)

Influencing factors and prognosis of aneurysmal SAH complicated with cerebral edema

  1. General Department of Neurological Diseases, West China Hospital of Sichuan University, Chengdu 610000, China
  • Online:2024-06-25 Published:2024-06-25

摘要: 目的 探讨影响动脉瘤性蛛网膜下腔出血(subarachnoid hemorrhage,SAH)并发脑水肿的危险因素,并对患者生存预后进行分析。
 方法 选取动脉瘤性SAH患者315例为研究对象,根据是否发生脑水肿将患者分为脑水肿组(n=78)及未发生脑水肿组(n=237),采用Logistic回归分析影响患者并发脑水肿的危险因素;根据改良Rankin评分(Modified Rankin Scale,mRS)将患者分为预后良好组(n=42)及预后不良组(n=36),采用Logistic回归分析影响患者预后不良的因素。
 结果 年龄≥60岁、颅内感染为动脉瘤性SAH并发脑水肿的独立危险因素(P<0.05);随访1年,36例患者预后不良,年龄、Hunt-Hess分级、CT Fisher分级、病灶数目为动脉瘤性SAH并发脑水肿患者预后不良的独立影响因素(P<0.05)。
 结论 高龄、颅内感染的动脉瘤性SAH患者应密切注意脑水肿的发生。对于高龄、Hunt-Hess分级Ⅲ~Ⅳ级、CT Fisher分级4级、病灶多发患者应关注预后情况,防止预后不良的发生。


关键词: 蛛网膜下腔出血, 脑水肿, 危险因素

Abstract: Objective To explore the risk factors and survival prognosis of aneurysmal subarachnoid hemorrhage (SAH) complicated with cerebral edema. 
Methods A total of 315 patients with aneurysmal SAH were enrolled as the research subjects, and they were divided into cerebral edema group (n=78) and non-cerebral edema group (n=237) according to occurrence of cerebral edema. Logistic regression analysis was used to analyze risk factors for cerebral edema in patients with aneurysmal SAH. The patients were divided into favourable prognosis group (n=42) and poor prognosis group (n=36) according to modified Rankin scale (mRS) score, and the factors affecting the poor prognosis of patients was analyzed by logistic regression analysis. 
Results Age ≥ 60 years and intracranial infection were independent risk factors for cerebral edema in patients with aneurysmal SAH (P<0.05). After 1-year follow-up, 36 patients had poor prognosis. Age, Hunt Hess grade, CT Fisher grade, and number of lesions were independent influencing factors for poor prognosis in patients with aneurysmal SAH complicated with cerebral edema (P<0.05). 
Conclusion Aneurysmal SAH patients with advanced age and intracranial infection should pay close attention to the occurrence of cerebral edema. For elderly patients with Hunt-Hess grade Ⅲ-Ⅳ, CT Fisher grade 4, and multiple lesions, clinicians should pay attention to the prognosis of patients and prevent the occurrence of poor prognosis. 


Key words: subarachnoid hemorrhage, cerebral edema, risk factors