Abstract: ［Abstract］ Objective〖HTSS〗To explore the correlation and predictive value of global acute coronary event registration(GRACE) score with cardiac troponin I(cTnI), brain natriuretic peptide(BNP) and glycosylated serum albumin(GA) levels in patients with non ST elevation myocardial infarction(NSTEMI).
〖WTHZ〗Methods〖HTSS〗A total of 153 NSTEMI patients admitted were selected as research objects. According to grace score, subjects were divided into three groups: high risk group(49 cases) Grace score >140, medium risk group(58 cases) Grace score 109-140, low risk group(46 cases) Grace score ≤108. The levels of cTnI, BNP and GA were measured in each group, and the occurrence of mace was followed up for 6 months. The predictive value of grace score, cTnI, BNP and GA levels to mace was analyzed by ROC.
〖WTHZ〗Results〖HTSS〗Single factor analysis of variance showed that the levels of cTnI, BNP and GA in patients with different grace risk grades were statistically significant(P＜0.01); the levels of cTnI, BNP and GA in high-risk group and middle-risk group were higher than those in low-risk group, while the levels of cTnI, BNP and GA in high-risk group were higher than those in middle-risk group, and the differences were statistically significant(P＜0.05). Grace score was positively correlated with cTnI, BNP and GA(P＜0.05). There were 12 cases of MACE in the high-risk group within 6 months after operation,5 cases in the middle-risk group and 1 case in the low-risk group, the difference was statistically significant(P＜0.05). The results of ROC curve analysis of 12 cases showed that AUC of grace score, cTnI, BNP and GA were 0.761, 0.674, 0.662 and 0.669 respectively, cut off value was 151.00, 3.83 mg/L, 340.72 μg/L and 20.01 respectively, sensitivity was 66.70%, 94.40%, 77.80% and 50.00%, specificity was 74.10%, 45.20%, 54.10% and 81.50%, Youden index was 0.408, 0.396, 0.374， 0.318, respectively.
〖WTHZ〗Conclusion〖HTSS〗Grace score is positively correlated with cTnI, BNP and GA levels in NSTEMI patients, and has predictive value and predictive value for mace, among which grace score had the highest predictive value.

Key words: myocardial infarction, troponin I, Natriuretic peptide, brain, serum albumin