Abstract: ［Abstract］ Objective〖HTSS〗To investigate the differences of prognosis and the clinical characteristics in patients with acute STsegment elevation myocardial infarction (STEMI) and thyroid dysfunction after propensity score matching.
〖HTH〗〖WTHZ〗Methods〖HTSS〗Forty patients with STEMI and hyperthyroidism after group percutaneous coronary intervention were recruited. By using the propensity score matching model and based on the patients with hyperthyroidism(1〖DK〗∶1), STEMI patients with hypothyroidism(n=40) and STEMI patients with normal thyroid function(n=40) during the same period were retrospectively collected. The clinical medication, length of hospitalstay, and complications were analyzed in the three groups. 
〖HTH〗〖WTHZ〗Results〖HTSS〗Significant differences were observed among three groups in E peak and left ventricular ejection fraction（P＜0.05）, and in receptor blockers and diuretics use（P＜0.05）. Compared with control group, the length of hospitalstay, the incidence of severe arrhythmia, atrial fibrillation, and heart failure in both hyperthyroidism and hypothyroidism group were significantly increased（P＜0.05）. Compared with hyperthyroidism group, hypothyroidism group had the longer length of hospitalstay and the higher incidence of severe arrhythmia, atrial fibrillation（P＜0.05）.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗For patients with acute STEMI and thyroid dysfunction after percutaneous coronary intervention, patients with hypothyroidism generally have a worse prognosis than patients with hyperthyroidism.

Key words: thyroid dysfunction, myocardial infarction, propensity score matching