Abstract: Objective To analyze the preventive effect of laparoscopic total hysterectomy(LTH) combined with round ligament suspension on postoperative pelvic floor dysfunction(PFD) in patients with uterine leiomyoma. 
Methods A total of 112 patients with uterine leiomyoma admitted to our hospital were divided into observation group(n=56) and control group(n=56) according to the random number table method. Patients in both groups were treated with LTH, and the observation group was combined with round ligament suspension. The PFD was compared in the two groups after different treatment. According to presence of PFD, the patients in the two groups were divided into the occurrence group and the non-occurrence group. The clinical records of the two groups were compared, and the risk factors of postoperative PFD were analyzed by Logistic regression model. 
Results After 6 months of follow-up, there were 38 patients with PFD. The incidence of frequent urination and stress urinary incontinence in the observation group was significantly lower than that in the control group(P＜0.05). The hospitalization days, exhaust time and PFIQ-7 score of the patients in the observation group were significantly lower than those in the control group(P＜0.05). Logistic regression analysis showed that diabetes(OR=2.208, 95%CI：1.457-3.345), number of pregnancies(OR=1.592, 95%CI：1.059-2.393), diameter of uterine leiomyoma(OR=2.545, 95%CI：1.076-6.016) and age(OR=2.358, 95%CI：1.275-4.364) were the risk factors for postoperative PFD(P＜0.05). 
Conclusion The risk factors of PFD in patients with uterine leiomyoma after LTH were diabetes mellitus, number of pregnancies and delivery, diameter of uterine leiomyoma and age type. LTH combined with round ligament suspension can reduce the risk of postoperative PFD.

Key words: leiomyoma, laparoscopy, hysterectomy