关键词: 脾切除术, 血栓形成, 危险因素

Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the causes of portal vein thrombosis and the influence of liver function scores in patients with splenectomy and pericardial devascularization.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Eighty patients with cirrhotic portal hypertension due to cirrhosis who underwent splenectomy and cardiac vascularization were selected. All patients′ liver function scores and other relevant data before and after surgery were retrospectively analyzed, and the possible causes of portal vein thrombosis were discussed and analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓After surgery, the levels of cholinesterase, total bilirubin and Child scores were significantly lower than those before surgery, and the difference was statistically significant(P＜005). After surgery, there were no significant differences in albumin, prothrombin time, cholinesterase, total bilirubin and Child score between two groups(P＞005). Ascites complication, surgical removal of spleen mass, postoperative red blood cell count, postoperative dimer level, postoperative portal vein diameter were higher or higher than nonthrombotic group, and postoperative portal vein velocity was lower than nonthrombotic group （P＜005）. Logistic regression analysis was performed with thrombosis as the dependent variable, postoperative ascites, surgical removal of spleen mass, postoperative red blood cell count, postoperative dimer, postoperative portal vein diameter, and postoperative portal vein velocity as independent variables. Increased postoperative dimer, increased postoperative portal vein diameter, and slow postoperative portal vein flowere risk factors for thrombosis.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The liver function of patients with splenectomy and pericardial devascularization is improved. The postoperative dimer level should be closely observed. The postoperative portal vein diameter and postoperative portal vein velocity should be detected to prevent thrombosis in the portal vein.

Key words: splenectomy, thrombosis, risk factors