Journal of Hebei Medical University

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Investigation on detection of cervical cancer and precancerous lesion by different testings  among women in poor rural areas#br#

  

  1. Department of Pathology, the People′s Hospital of TangXian, Hebei Province, TanXian 072350, China
  • Online:2018-04-25 Published:2018-04-23

Abstract: [Abstract] Objective〖HTSS〗〓To study the detection plans of cervical cancer by different testings among rural women in Tangxian,Baoding, and to provide treatment reference of cervical cancer for local.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The Thinprep cytologic test, Human papilloma virus(HPV) test, colposcopy and biopsy were performed among 5 587 women in outpatient center of gynecologic department from May 2016 to May 2017. Thinprep liquid based cytology was chosen for cytology, In situ hybridization immunofluorescence system applied for hr HPV test.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓A total of 5 587 outpatient visits to women were screened for opportunistic age in a year, aged 18-65 years, average(38.54±4.43) years. The cervical intraepithelial neoplasia 2(CIN2) or greater lesion diagnosed by cotesting(5.199%) was higher than that of hr HPV test (3.539%)and cytology(1.299%)(P<005). Differences are statistically significant. The sensitivity of the cotesting  was higher than that of hr HPV test and cytology(P<005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The CIN2 or greater lesions diagnosed by cotesting was higher than that of cytology and hr HPV test. The cotesting could provide more reference for management of abnormal results of cervical screening and very helpful in prevention and treatment. But the testing method should be combined with the specific situation of each patient, and make the best screening program suitable for them.

Key words: uterine cervical neoplasms, rural population, screening