Abstract: Objective To explore the predictive value of blood routine parameters for catheter-related bloodstream infection in patients undergoing hemodialysis. 
Methods A total of 107 patients with end-stage renal disease (ESRD) who underwent maintenance hemodialysis (MHD) and suspected catheter-related bloodstream infection (CRBSI) in the wards and outpatients in Department of Nephrology of our hospital were retrospectively selected as subjects. The blood routine and procalcitonin data were obtained within 48 h of fever. The white blood cells (WBC) and procalcitonin were used as reference. The predictive value of hematocrit (HCT), mean corpuscular volume (MCV), mean corpsularhemoglobin (MCH), mean corpsularhemoglobin concentration (MCHC), red blood cell distribution width (RDW), platelet distribution width (PDW), plateletcrit (PCT), mean platelet volume (MPV), platelet-larger cell ratio (P-LCR), and derived parameters neutrophil/lymphocyte value (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) for occurrence of CRBSI was evaluated. 
Results Compared with non-CRBSI group, WBC and procalcitonin in CRBSI group were significantly higher than those in non-CRBSI group (P＜0.05). RDW, PCT, P-LCR %, NLR, PLR and PDW in CRBSI group were significantly increased (P＜0.05), while MCV was significantly decreased (P＜0.05). WBC, procalcitonin, RDW, PDW, P-LCR and NLR had certain predictive value for the occurrence of CRBSI (P＜0.05). When NLR was> 6.78, the sensitivity and specificity of CRBSI prediction were 43.32% and 86.72% respectively, and when P-LCR was＞43.67%, the sensitivity and specificity of CRBSI prediction were 70.04% and 66.72% respetively. When PDW was ＞8.84 fL, the sensitivity and specificity of CRBSI prediction were 56.73% and 90.03%respectively, and when RDW was >58.23, the sensitivity and specificity of CRBSI prediction were 73.45% and 66.78% respectively. When at least two of the NLR, P-LCR, PDW and RDW exceeded the corresponding truncation value, the AUC for predicting the occurrence of CRBSI was 0.829, the sensitivity was 76.67%, and the specificity was 73.33% (P=0.001). 
Conclusion Four parameters, including RDW, PDW, P-LCR and NLR, have certain predictive value for the occurrence of CRBSI. In terms of NLR>6.78, P-LCR＞43.67, PDW＞8.84 fL, RDW＞58.23 fL, at least two of the above four parameters have high predictive value for CRBSI.

Key words: renal dialysis, catheter-related bloodstream infections, blood routine parameters