河北医科大学学报

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脑瘫危险因素调查#br#

  

  1. 1.中国人民武装警察部队总医院神经内科,北京 100039;2.中国人民武装警察部队总医院儿科,北京 100039
  • 出版日期:2018-10-25 发布日期:2018-09-27
  • 作者简介:李敏(1978-),女,河北保定人,中国人民武装警察部队总医院主治医师,医学博士,从事神经内科疾病诊治研究。

Investigation of risk factors for cerebral palsy#br#

  1. 1.Department of Neurology, Chinese People′s Armed Police General Hospital, Beijing 100039, China;
    2.Department of Pediatric, Chinese People′s Armed Police General Hospital, Beijing 100039, China
  • Online:2018-10-25 Published:2018-09-27

摘要: [摘要]〓
〖HTH〗目的〖HTSS〗〖KG*2〗明确脑瘫的高危因素, 从而避免或者减少脑瘫的发生。
〖HTH〗方法〖HTSS〗〖KG*2〗选择就诊的脑瘫患者795例,进行回顾性调查和分析,筛选脑瘫的高危因素。
〖HTH〗结果〖HTSS〗〖KG*2〗脑瘫组母亲怀孕时年龄高于对照组,孕周少于对照组,脑瘫组患儿出生时的体重低于对照组,多胎、孕期感染、出生时窒息缺氧(窒息时间超过5 min)、早产、新生儿惊厥、新生儿败血症、生后黄疸发生率高于对照组,差异均有统计学意义(P<005)。多因素Logistics回归分析结果显示,多胎、孕期感染、出生时窒息缺氧史、早产、低出生体重、新生儿惊厥、新生儿败血症、生后黄疸及母亲怀孕时年龄是脑瘫发病的危险因素。
〖HTH〗结论〖HTSS〗〖KG*2〗多胎、孕期感染、出生时窒息、早产、低出生体重、新生儿惊厥、新生儿败血症、生后黄疸、母亲怀孕时高龄是脑瘫的危险因素。

关键词: 脑性瘫痪, 危险因素, Logistic模型

Abstract: [Abstract]〓Objective〖HTSS〗〓To investigate the highly risk factors of cerebral palsy in order to avoid or reduce the occurrence of cerebral palsy.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓This was a retrospective investigation and analysis performed in a total of 795 children with cerebral palsy and further screened the highly risk factors of cerebral palsy.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The mother′s pregnant age in cerebral palsy group was higher than the control group, the gestational age was less than the control group, the group of children with cerebral palsy birth weight was lower than the control group. The incidence of multiplets, infection during pregnancy, birth asphyxia anoxia(suffocation time more than 5 min), preterm birth, neonatal convulsion, neonatal sepsis, postnatal jaundice in cerebral palsy were higher than the control group, and the difference was statistically significant(P<005). Multiple factors Logistics regression analysis shows that the multiplets, history of infection during pregnancy, birth asphyxia anoxia, premature birth, low birth weight and neonatal convulsions, neonatal sepsis, jaundice after birth, and advanced age during pregnant were  risk factors for the onset of cerebral palsy.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The results showed that neonatal convulsion, asphyxia at birth, low body weight at birth, infection during birth and the advanced maternal age can increase the incidence of CP.

Key words: cerebral palsy, risk factors, Logistic models