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中文
Table of Content
25 February 2016, Volume 37 Issue 2
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Gestationalage-specificreferenceintervalsformaternalthyroid functioninShijiazhuangGaoxinarea
ZHOU Weiling1, WANG Yuan1*, GAO Qian1, ZHANG Huixin2， ZHANG Ruifang1, LIU Yunfei1
2016, 37(2): 125-128. doi:
10.3969/j.issn.10073205.2016.02.001
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Objective Toestablishthegestationalmonth-specificstage ( firsttrimesterof
pregnancy , secondtrimesterofpregnancy , thethirdtrimesterofpregnancy ) referenceintervals
formaternalthyroidfunctionintheareaofShijiazhuangGaoxinarea.Methods Atotalof120
pregnantwomenand60non-pregnantwomenwereselectedaccordingtothestrictcriteria.The
studymeasuredmaternalthyroidfunction.Thenormalreferenceintervalsofpregnancyspecific
serumfreetriiodothyronine ( FT 3 ), freethyroxine ( FT 4 ), thyroidstimulatinghormone ( TSH )
wereestablished.Results Serum FT 3 , FT 4 , TSHlevelswerequitedifferentbetweennon-
pregnantwomenandpregnantwomen ( P <0.01 ) .Comparingwiththereferenceintervalsfor
maternalthyroidfunctionlevelofnon-pregnantwomen , theserumFT 4 wassignificantlyhigher
andTSH waslowerinthe1sttrimesterofpregnancy ( P <0.05 ); theserumlevelofFT 3 and higherinthe2ndtrimesterofpregnancyand3rdtrimesterofpregnancy ( P <0.05 ) .Comparing
withthereferenceintervalsformaternalthyroidfunctionof2ndtrimesterofpregnancy , the
serum FT 4 waslowerand TSH washigherinthe3rdtrimesterofpregnancy ( P <0.05 ) .
Conclusion Referenceintervalsforthyroidfunction werequitedifferentbetween pregnant
womenandnon-pregnantwomen , anditwasquitedifferentindifferenttrimestersofpregnancy.
TSH werelowerinthe2sttrimesterofpregnancy ( P <0.05 ); theserumFT 3 andFT 4 werelower
inthe3sttrimesterofpregnancy ( P <0.05 ) .Comparingwiththereferenceintervalsformaternal
thyroidfunctionof1sttrimesterofpregnancy , theserumFT 3 andFT 4 werelowerandTSH was
ThecurativeeffectandinfluenceofserumhsCRPandVEGFofpatientswithischemic#br# cardiomyopathyandheartfailurewithSofrenInjection
SHIHui-rong1,WANGDe-wei 1,ZHAODan-dan2,LIUGuo-hong1,LIU Quan-liang3,HUANGJie
2016, 37(2): 129-132. doi:
10.3969/j.issn.10073205.2016.02.002
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Objective Toexplorethecurativeeffectandsignificanceofserum high-
sensitivityC-reactiveprotein ( hsCRP ) andvascularendothelialgrowthfactor ( VEGF ) ofpatients
withischemic cardiomyopathy and heartfailure with Sofren injection , to investigateits
pharmacologicaleffects.Methods Onehundredandtwentypatientswererandomlydividedinto
twogroups , 59casesasSofrengroupand61casesascontrolgroup.Thetwogroupsweregiven
conventionaltherapy.TheSofrengroupwasgivenSofrenInjection10 mL / dintravenousdrip
basedonroutinetreatment.Thetwogroupsweretreatedfor2 weeks.Thenleftventricular
ejectfraction ( LVEF ), leftventricularinternaldiameteratend-diastole ( LVIDd ) andthecontent ofserumB-typenatriureticpeptide ( BNP ), hsCRPandVEGFofthetwogroupswereanalyzed.
Results Comparedwiththepretreatment , thecontentofserumBNPandhsCRPoftheSofren
groupandthecontrolgroup weredecreased ( P <0.05 ), LVEFandtheserum VEGF were
increased ( P <0.05 ), LVIDdofthesafrengroupwasdecreased ( P <0.05 ), buttherewasno
significantdifferenceinLVIDdwiththecontrolgroup ( P >0.05 ) .LVIDdandcontentofserum
BNPandhsCRPofSofrengroupwerealllowerthanthoseofcontrolgroupafter2weeksof
treatment ( P <0.05 ), LVEFandthecontentofserum VEGF wereallhigherthanthoseof
controlgroupafter2weeksoftreatment ( P <0.05 ) .Conclusion SofrenInjectioncanimprove
thesymptomsofpatientswithischemiccardiomyopathandheartfailure , decreasethecontent
serumBNPandhsCRPquickly , increaseLVEFandthecontentserum VEGF.Themechanism
mayberelatedtotheblockinginflammatoryreactionofatherosclerosis.
GeneticpolymorphismofglutathioneS-transferasezeta1amonghealthy#br# HanpopulationinHebeiprovince
FANZhi-liang1,2,FENGXiao-juan 3,LIChun-yan 2,YINShao-hua1, TIANXin-ying 2*,REN Wen-bo
2016, 37(2): 133-136. doi:
10.3969/j.issn.10073205.2016.02.003
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Tostudythe glutathione S-transferasezeta1 ( GSTZ1 ) genetic
polymorphismsamonghealthyHanpopulationofHebeiprovince.Methods Usingpolymerase
chainreaction-restrictionfragmentlengthpolymorphism ( PCR-RFLP ) todetectthegenotypesof
GSTZ1Lys32Gluin210healthy Hanpopulationof Hebeiprovince.Results Thegenotype
distributionofthehealthy HebeiHanpopulationisconsistentwith Hardy-Weinberggenetic
equilibriumlaw.ThedistributionsofbothgenotypefrequencyandallelefrequencyofGSTZ1
Lys32Gluin Hebeihealthy Hanpopulationaresignificantlydifferentfrom thoseinIranian ,
Australian , GermanandAmerican ( P <0.05 ) .Thedistributionsofbothgenotypefrequencyand allelefrequency of GSTZ1 Lys32Gluin Iranian are significantly differentfrom thosein
Australian , Germanand American ( P <0.05 ), however , therearenosignificantdifference
amongAustralian , GermanandAmericaninthedistributionsofbothgenotypefrequencyand
allelefrequencyofGSTZ1Lys32Glu ( P >0.05 ) .Conclusion Thedistributionsofbothgenotype
frequencyandallelefrequencyofGSTZ1Lys32Gluin Hebeihealthy Hanpopulationownits
characters.ThedistributionsofGSTZ1Lys32Gluinregionsandracesaresignificantlydifferent.
Comparisonofthreetypesofinternalfixationforunstablepelvicfractures : afiniteelementanalysis
CUIYun-wei,WUTao,LISheng,CHEN Wei,XINGXin,ZHANGYing-ze*
2016, 37(2): 137-142. doi:
10.3969/j.issn.10073205.2016.02.004
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] Objective Tobuildanormalpelvicfiniteelementmodelandtocomparethe
stabilityofunstablepelvicfracturesfixedwiththreekindsofinternalfixatorbythree-dimensional
finiteelementanalysis.Methods A normaladultmalewaschosenrandomlyandscannedby
computerizedtomography ( 1mmslicethickness ) .Theresultswereconservedindigitalimaging
andcommunicationsinmedicineformat.Thefiniteelementmodelwasmadeusingthesoftwareof
Mimics , GeomagicStudio , SolidWorks , Abaqus.Thefiniteelementmodelofunstablepelvic
fracturewassetup , andthefractureofposteriorpelvicringwasfixedwiththreekindsofinternal
fixatorseparately.Aloadingof500Nwasputandthebilateralacetabulumwasconstrained.The
strain , displacementandstressnephogramsofthepelvicmodelandtheshiftoffracturegapwere
obtained.Results Under500 N verticalload , thestresspassedthroughsacrum , bilateral sacroiliacjointandthearcuatelinetothebilateralacetabulum.Under500Nverticalload , the
strainconcentratedofthe modelwasverysmall.Thedisplacementsofpelvic model were
iliosacral ( IS ) model ( 1.86mm ), minimallyinvasiveadjustableplate ( MIAP ) model ( 6. 89mm ),
tensionbandplate ( TBP ) model ( 9.10 mm ) .TheshiftoffracturegapinpelvicmodelwasIS
model ( 1.75mm ), MIAPmodel ( 3.00mm ), TBPmodel ( 8.03mm ) .Conclusion Thepelvisisa
steadystructure.Underverticalload , thestabilityoftheunstablepelvicfracturesfixedwith
MIAPislessthanthatfixedwithtwoISscrews , andbetterthanthatfixedwithTBP.
Treatingpatientswithlumbartuberculosisbykeepingscleroticboneuniformlydrilledjoint#br# withimplantingallograftiliacboneforinterbodyfusion
DONGZhao-liang1,LIYe-tong2,JIAChen-guang1,YAOXiao-wei1,LIZhuo1,LIUFeng-sheng1*
2016, 37(2): 143-146. doi:
10.3969/j.issn.10073205.2016.02.005
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Toinvestigatethevalueoftreatingpatientswithlumbartuberculosis
bykeepingscleroticboneuniformlydrilledjointwithimplantingallograftiliacboneforinterbody
fusion.Methods Therewere47patientswithlumbartuberculosisinthisretrospectivestudywho
weretreatedbysurgeryofkeepingscleroticboneuniformlydrilledjointwithimplantingallograft
iliacboneforinterbodyfusion.Results Postoperativefollow-upwere16-24 months.Forty-
sevenpatientswithlumbartuberculosiswereallcured.Thebonyfusiontimeof47patientswas6
monthsto12months.Inaccordancewiththestandardofbonefusion , theresultswereexcellent
in37cases , goodin8cases , fairin2cases , andpoorin0case.Kyphosisin25caseswithCobb
anglehavebeenfound , 2weeksafterthesurgeryandthefinalfollow-up , thekyphoticdeformity
werecorrected , andthe difference wasstatistically significant ( P <0.01 ) .The patients'
neurologicalfunctionswereelevatedinvaryingdegrees.TheFrankelgradingshowedthat : 1case
wasrecoveredfromgradeAtogradeC , 1casewasrecoveredfromgradeCtogradeE , 1case
wasrecoveredfromgradeCtogradeD , and3caseswererecoveredfromgradeDtogradeE.
Conclusion Goodsurgicaloutcomeshavebeenfoundinthisstudyandthetechniquethattreating
patients with lumbartuberculosis by keeping sclerotic bone uniformly drilledjoint with
implantingallograftiliacboneforinterbodyfusioncouldbeappliedfurtherintheclinicaltrial.
Theexpressionandcorrelationofp-mTOR , eIF4Eandp-4EBP1ininvasivepituitaryadenomas
LIPeng1, ZHANGQing-jiu 2*,LIXu-run 3,MAFa 3,LIULan 4,LIXiao-yan 5
2016, 37(2): 147-150. doi:
10.3969/j.issn.10073205.2016.02.006
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Objective Toevaluatetheexpressionandcorrelationofphosphorylatedmammal
ofrapamycin ( p-mTOR ), eukaryoticinitiationfactor4E ( eIF4E ) andphosphorylatedeukaryotic
initiationfactor4Ebindingprotein1 ( p-4EBP1 ) ininvasivepituitaryadenomas.Methods Fifty-
twopatientsofinvasivepituitaryadenomasandforty-ninepatientsofnon-invasivepituitary
adenomaswereselectedinthisstudy.Theexpressionsofp-mTOR , eIF4Eandp-4EBP1were
respectivelydetectedininvasivepituitaryadenomasgroupandnon-invasivepituitaryadenomas
groupbyimmunohistochemistry method.Thedifferencesofp-mTOR , eIF4E and p-4EBP1
betweenthetwogroupswerecompared , andthecorrelationofp-mTOR , eIF4Eandp-4EBP1in
invasivepituitary adenomas wasstudied.Results The positiverate oftheexpression of
p-mTOR , eIF4Eandp-4EBP1 wasrespectivelyhigherininvasivepituitaryadenomasgroup
(
73.08% , 63.46% , 67.31% ) thanthatinnon-invasivepituitaryadenomas ( 48.98% , 38.78% ,
36.73% ) .Thedifferencesbetweentwogroupswerestatisticallysignificant ( P <0.05 ) .Positive
correlation wasfounded betweenthe expression ofp-mTOR , eIF4E ininvasive pituitary
adenomas ( r =0.520 , P =0.000 ), and positivecorrelation wasalsofounded betweenthe
expressionofp-mTORandp-4EBP1ininvasivepituitaryadenomas ( r =0.360 , P =0.041 ) .In
addition , positivecorrelation wasfoundedbetweeneIF4Eandp-4EBP1ininvasivepituitary
adenomas ( r =0.320 , P =0.019 ) .Conclusion Theexpressionlevelsofp-mTOR , eIF4Eand
p-4EBP1oftheinvasivepituitaryadenomaswerehigherthanthatofthenon-invasivepituitary
adenomas.Positivecorrelation wasfoundedamongp-mTOR , eIF4Eandp-4EBP1ininvasive
pituitaryadenomas.p-mTOR , eIF4E and p-4EBP1inthepituitaryadenoma may playan
importantroleintheinvasivenessofpituitaryadenomas.
Comparative study of transumbilical single hole and double hole laparoscopic repair of peptic ulcer perforation
KANGChun-bo,MENGQing-cheng,LIXiao-wei,LIXu-bin,ZHANGQian,QUJun
2016, 37(2): 150-153,165. doi:
10.3969/j.issn.10073205.2016.02.007
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] Objective Tosearchforabettermethodforlaparoscopicrepairofpepticulcer
perforation.Methods Retrospectiveanalyzed37casesunderwentlaparoscopicrepairofpeptic
ulcerperforation , thetransumbilicalsingleholegroup ( 15cases ), thedoubleholeslaparoscopic
group ( 22cases ) .Comparativeanalysisofthetransumbilicalsingleholegroupandthedouble
holeslaparoscopic group ofpatients with operationtime , intraoperative bleeding volume ,
postoperativefastingtime , liedinbedtime , hospitalizationtime , analgesicuse.Results The
operationtime , postoperativeexhausttimeandhospitalizationtimeofdoubleholeslaparoscopic
groupweresignificantlyshorterthanthoesofsingleportlaparoscopicgroup ( P <0.05 ); The
incisioninfectionofdoubleholeslaparoscopicgroupwassignificantlyreducedthanthatofsingle
holelaparoscopicgroup ( P <0.05 ); Theamountofintraoperativebleeding , analgesicuseandthe
mortalityratebetweenthetwogroupshadnosignificantdifference ( P >0.05 ) .Conclusion
Doubleholeslaparoscopicrepairwasmoreconvenientandmoresafetythantransumbilicalsingle
portlaparoscopicrepairofpepticulcerperforation , theoperationtimewasshorter , theincision
infectionratewaslower , therecoverytimeofintestinalperistalsisandthehospitalizationtime
wereshorter.
Screeningresultsanalysisofcervicalcancerandbreastcanceramongrural#br# womeninpartialcountiesofHebeiprovince
WANGYa-fan,LIUXiao-xu,MOZhong-fu,DONGXin,DUJuan,QINLi-xin
2016, 37(2): 154-157. doi:
10.3969/j.issn.10073205.2016.02.008
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Objective Tounderstandtheprevalenceofcervicalcancerandbreastcancer
amongruralwomenin9countiesofHebeiprovince , andprovideevidenceforthepreventionand
controlofthem.Methods Atotalof50667ruralwomenin Hebeiamong35-65yearsold
receivedcervicalcancerscreeningusingthinprepcytologytest ( TCT ) .Thenfurthercolposcopy
andbiopsypathologyweredoneamongthewomenwithsuspectorabnormalresultsofcastoff
cellsexamination.Atotalof8177 womenamong25-55yearsoldreceivedbreastcancer
screeningusinggalactophorevisualexamination , alpatio , ColorDopplerimaginganddiagnoseof
mammography.Results 1672womenwerefoundabnormalwithTCT , accountingfor3.30%
(
1672 / 50667 ) .Thedifferencebetweenthegroups wasstatisticallysignificant ( P <0.01 ) .
Cervicalintraepithelialneoplasiaweredetectedin106women ( 0.21% ) andcervicalcancerwas
foundin8women ( 0.02% ), thedifferencehadnosignificance ( P >0.05 ) .Eightwomenwere
diagnosedasbreastcancer , accountingfor0.10% ( 8 / 8177 ) .Conclusion Theprevalenceof
cervicalcancerandbreastcancerwerelowamongruralwomeninHebeiprovince.Thescreening
rateshouldbeincreased.Atthesametime , healtheducationaboutthesediseaesdiseasesshould
bestrengthenedforruralwomen , toimprovetheirhealthcareconsciousness.
Toevaluatetheclinicaleffectofthreekindsofzirconiacrownsofposteriorteethinfiveyears
XINZhi-qiang 1, LIANGRui-ying 3, YANGChun-xia3
2016, 37(2): 158-160,171. doi:
10.3969/j.issn.10073205.2016.02.009
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] Objective Toevaluatetheclinicaleffectofthreekindsofmaterialsofzirconia
crownsofposteriorteethin5years.Methods The240requiredcrownsofposteriorteethwere
dividedintothreegroups : Cerconzirconiagroup , WielandzirconiagroupandIrelandzirconiaall-
ceramiccrownsgroup.Eachgroupincluded80teeth.After5yearsofclinicalobservation , clinical
effectofdifferentgroupswasevaluated.Results Therewerenosignificantdifferenceamongthe
threegroupsinrepairsuccessrate 、 fractureincidencerate 、 theincidenceofmildgingivitis 、
measurementofedgedensity ( P >0.05 ) duringclinicalobservationof5years.Conclusion Three
kindsofzirconiacan be used asanidealtooth crown material , which meettheclinical
requirements.
EffectofBcl-2familyonapoptosisofsalivaryadenoidcysticcarcinomacell#br# lineACC-Minducedbysulforaphane
IAZhi-yu1,GUOTao2,ZHUANGZhi-zheng3,YUELei1,YANG Wei1,HANGYing-huai1*
2016, 37(2): 161-165. doi:
10.3969/j.issn.10073205.2016.02.010
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Objective Tostudytheeffectofsulforaphane ( SFN ) onexpressionofBcl-2
familyinsalivaryadenoidcysticcarcinomacelllineACC-M , andtoevaluatetheeffectofBcl-2
familyonapoptosisofACC-McellsinducedbySFN.Methods AfterACC-Mcellsweretreated
with20or40 μ mol
/ LSFNfordesiredtime , morphologychangesofACC-Mcellswereobserved
withinversionphasecontrastmicroscope , Giemsastainingandtransmissionelectronmicroscope
( TEM ) .FlowcytometrywithAnnexin-V-FITC / propidiumiodidedoublestainingwereusedto
detecttheapoptosisrateofACC-M.AfterACC-Mcellsweretreatedwith40 μ mol
/ LSFNfor4 ,
8 , 16and24hours , theexpressionofBax , Bak , Bcl-2andBcl-xLweredetectedbyWesternblot.
Results ImagedatashowedthatSFNcouldinduceapoptosisofACC-Mcells.Flowcytometry datashowedthatapoptosisratewasincreasedwithtimeandconcentrationofSFN.Therewere
significantlydifferentamongeachgroups ( P <0.05 ) .ExpressionofproapoptosisproteinBaxand
Bakas wellasratioofBax / Bcl-2 wereincreased withtreatingtime , whereasthatofanti-
apoptosisproteinBcl-2andBcl-xLweredecreasedbytreatmentwith40 μ mol
/ LSFNfor4 , 8 , 16
and24h.Thereweresignificantlydifferentamongeachgroups ( P <0.05 ) .Conclusion SFN
couldinduceapoptosisofACC-Mcellswithtime-andconcentration-dependentmanners , andup-
regulateexpressionsofBaxandBak , anddown-regulateexpressionsofBcl-2andBcl-xL , which
mightbethemechanismsfortheapoptosisofACC-MinducedbySFN.
ComparativeobservationofEpi-LASIKandFlap-freeEpi-LASIKforlow-to-moderatemyopia
ComparativeobservationofEpi-LASIKandFlap-freeEpi-LASIKforlow-to-moderatemyopia
2016, 37(2): 166-170. doi:
10.3969/j.issn.10073205.2016.02.011
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Objective Tocomparetheclinicalefficacyofepipolislaserin-situkeratomileusis
(
Epi-LASIK ) andflap-freeEpi-LASIKincorrectionoflow-to-moderatemyopia.Methods Thirty
patients ( sixtyeyes ) withsphericalequivalentlessthan -6.
0D wereenrolled.Werandomly
choseoneeyeapplyingEpi-LASIK , andtheotheroneapplyingflap-freeEpi-LASIK.Afterthe
operation , wecomparedthepostoperativeocularirritationsymptoms , healtimeofcorneal
epithelial , visualacuity , diopter , occurrenceofhaze , cornealtopography ( ISVandIVA ) and
higher-orderaberration ( RmSh , ComaandSA ) .Results Thepostoperativeirritationsymptoms
andhealtimeofcornealepithelialwithflap-freeEpi-LASIK werelessandshorterthanEpi-
LASIK ( P <0.05 ) .Therewasnodifferenceinform ofdiopter , hazeformation , ISV , IVA ,
RMSh , ComaandSA betweenflap-freeEpi-LASIKandEpi-LASIK ( P >0.05 ) .Atthefirst
week , thevisualacuityofflap-freeEpi-LASIK wasbetterthanthatofEpi-LASIK.Butthe
differenceofvisualacuitybecamenosignificantatthethirdmonth ( P >0.05 ) .Conclusion Flap-
freeEpi-LASIKyieldedlesspostoperativeirritation , lessrecovertimeofcornealepithelialand quickerrecoveryofnakedeyevisualacuity.Thefateofcornealepithelialflapdidnotaffectthe
long-termoccurrenceofhaze.BothofEpi-LASIKandflap-freeEpi-LASIKyieldedgoodvisual
qualityafter3monthswithbettervisualqualityandstablerefraction.
Clinicalanalysisofthemodifiedlacrimalductintubationsystemintreatmentof#br# childrenwithrefractorylacrimalductobstruction
HANLi-po,ZHANGYu,WANGFeng-xian,CHEN Hui-ning,WANGSu-mei
2016, 37(2): 171-174. doi:
10.3969/j.issn.10073205.2016.02.012
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Objective Tostudytheeffectofwiretypelacrimalductdilatationcombinedwith
lacrimalductintubationoperation in treatment of children with refractory lacrimal duct
obstruction , andtoanalysizerelatedfactorsaffectingthecurerateinchildren'srefractory
lacrimalductobstruction.Methods Intreatmentofrefractorylacrimalductobstruction , 306
cases ( 426eyes ), theaveragedageof1yearsold , followed-upfor3-18monthswerecollected.
Thosepatientsweretreatedbysawtypelacrimalductexpansioncombinedwithlacrimalduct
intubationsurgeryinthedepartmentofophthalmologyofBaodingchildren'shospital.Analysis
theinfluence ofpatientageand preoperativetreatmenton curerate.Pearson correlation
coefficientwasusedforstatisticalanalysis.Results Intotalof306cases ( 426eyes ), 386eyes
werefittedwithcriterionofcure.Thetotalcureratewas90.6% ( 386 / 426 ) .Theagefactor : the
cureratein6~12monthsgroups , 12monthsto24monthsgroups , 24monthsto36months
groups , andmorethan36monthsgroups , thecureratewas96.6% (
112 / 116 ), 91.3%
(
168 /
184 ), 86.0% ( 74 / 86 ), 80.0% ( 32 / 40 )( r =-0. 960 , P =0.002 ) .Preoperativetreatmentfactors :
thecurerateinprobingoflacrimalpassageafterfailureofchildren , childrenwithpurelacrimal
ductintubationfailedafter2groupswere : 93.6% ( 322 / 344 ), 78.0% ( 64 / 82 )( P =0.004 ) . Conclusion Treatmenteffectinwiretypelacrimalductdilatationcombinedwithlacrimalduct
intubationoperationforchildrenwithrefractorylacrimalductobstructionwasobvious , andwith
highsecurity.Thecureratewasdecreased withtheincreaseofage.Sawtypelacrimalduct
dilatationcombined withlacrimalductintubationtreatmentsignificantlyimprovedtreatment
effectscomparetosimplelacrimalintubationforpostoperativeeffectofinchildren withthe
probingoflacrimalpassagefailure.
HRCTstudybasedonCTPAinpulmonaryembolism
BAIDong,ZHUAn-hui,ZHENGJia-tang,WANG Ming-liang,CHENJie,ZHANGXiao-jin*
2016, 37(2): 175-178,182. doi:
10.3969/j.issn.10073205.2016.02.013
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Objective To evaluatethe diagnostic value of high-resolution computed
tomography ( HRCT ) based on computertomography pulmonary angiography (
CTPA ) in
pulmonaryembolism ( PE ) .Methods Retrospectivelyanalyzed CTPA andthechest HRCT
imagesbased onthereconstruction of CTPA from 73 patients with suspected pulmonary
embolism.AccordingtotheresultsofCTPA , allcasesweredividedintoembolismgroupand
non-embolism group.The CTPA and chest HRCT images betweenthetwo groups were
compared .Theradiographicsighsofpulmonary embolism with statisticsignificance were
concluded.Results Atotalof73patients , diagnosedwithPEin25 , ruledoutofPEin48.The
twogroupsdidnothaveanysignificantdifferenceintheage , sexofthepatients , andthenumber
ofthebronchiwithembolisminleftandrightlung , respectively.Thepercentageofperipheral
pulmonaryembolism was much morethancentralpulmonaryembolism.Thecentraltype
embolismwastwotimesmorethanthetotalofothertypesofembolism.Pleuralthickeningand
consolidationsignswerebothhighlycommon.HRCT pulmonaryhypertensionsuggestedthe
possibilityofpulmonaryembolismwasabout3. 29timesthanthatofthepatientswithpulmonary
hypertension , pulmonaryhypertensionhadpredictivevaluefortheoccurrenceofpulmonary
embolism.Conclusion Withthecharacteristicsofquick , non-invasiveandhighsensitivity , reconstructedchestHRCTwhentakenCTPAatthesametime , whichcouldbeusedtoassessin
realtimewhethertherewereotherbasicdiseaseofthelunginordertoimprovethevalueof
CTPAdiagnosisandavoidadditionalradiationcausedbysecondarychestCTexamination.
Effectcomparisonofdifferentvolumesof0.25%evobupivacainehydrochlorideonnerve#br# branchesofaxillarybrachialplexusblockinchildren
WANGJin-bao,ZHANGZai-wang,WANGQi,YANGXiao-min
2016, 37(2): 179-182. doi:
10.3969/j.issn.10073205.2016.02.014
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Objective To compare the effects of different dose volume of 0.25%
evobupivacaine hydrochloride on nerve branches of axillary brachial plexus block under
ultrasound-guidedinchildren.Methods Atotalof120 ASA Ⅰ or Ⅱ childrenscheduledfor
surgeryofthehandorforearm wererandomlydividedinto4groups ( Groups0.35mL /
kg
,
0.30
mL /
kg
,
0.25mL /
kg
,
0.20mL /
kg
) .Midazolam wasadministered30minbeforetheoperating ,
propofolwasgivenbytarget-controlledinfusion ( TCI ) startedatentering , whenthepatientslost
consciousnesandhadnoreactiontoverbalinstructions.Axillaryroadblockbrachialplexuswas
done.0.35mL /
kg
, 0.30mL /
kg
, 0.25mL /
kg
, 0.20mL / kgoflocalanestheticswereequally
injected adjacent to radial nerve , median nerve , ulnar nerve , musculocutaneous nerve
respectively.Nerveblockeffect , duration , generalanesthesiadrugsdosageofeachgroupwere
observated , which wasusedtoevaluateperioperativeanesthesiaresults.Results Therewas
significantlydifferenceinefficancyofnerveblockinginfourgroups ( P <0.05 ) .Thecaseswhich
neededketamineingroup0.20mL / kgweremorethanthatinothergroups.Comparedtogroup
0.35mL /
kg
, 0.30 mL / kgand0.25 mL /
kg
, group0.20 mL / kgshoweda worseanalgesia
afficancyandshort-timetolerance ( P <0.05 ) .Conclusion Itprovidedanactiveamplifierbyusing
thevolumefrom 0.25 mL / kgto0.35 mL / kgofbupivacaineforultrasound-guidedaxillary
approachbrachialplexusblockinupperlimbssurgeryinchildren.
Comparative study of using different levels of positive endexpiratory pressure with dexmedetomidinebased sedation regimen after offpump coronary artery bypass grafting
SUN Wen-bo,ZHANGLi-min,WUChun-ling,LIRui
2016, 37(2): 183-186. doi:
10.3969/j.issn.10073205.2016.02.015
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] Objective Toevaluatetheuseofdexmedetomidine-basedsedationregimenon
differentlevelsofpositiveend-expiratorypressure ( PEEP ) afteroff-pumpcoronaryarterybypass
grafting ( OPCABG ) .Methods Thisisanopenprospectivestudy with60consecutiveadult
patientsafterOPCABGontheuseofdexmedetomidine-basedsedationregimenundervolume-
controlledmechanicalventilation ( VCV ) withdifferentPEEP , dividedintothreegroups ( Group
A : PEEP= 0cmH 2 O , GroupB : PEEP= 5cmH 2 O , GroupC : PEEP= 10cmH 2 O ) .Results
Fromthepointofweaningfrom mechanicalventilationuntil12hoursafterOPCABG , compared
withGroupAandB , theapplieddoseofdexmedetomidinewasincreased ( P <0.05 ), average
mechanicalventilationwasshorten ( P <0.05 ), durationinICUandhospitalwasshorten ( P <
0.05 ), andPaO 2 atpostoperative12hand24hwasincreased ( P <0.05 ) inGroupC.Conclusion
PEEPat10cmH 2 Ocansignificantlyimproveprognosis.HigherlevelofPEEPrequired more
dexmedetomidine , but the patients were associated with shorter duration of mechanical
ventilationinpostoperativeOPCABGpatients.
MethodologicalstudyofSensititertuberculosisdrugsensitive#br# plateindetectingmycobacteriumtuberculosis
WANG Hao1,ZHAOQing2,CHEN Mei-hong1*
2016, 37(2): 187-190. doi:
10.3969/j.issn.10073205.2016.02.016
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ThepresentstudyisdesignedtoevaluateSensititre tuberculosis
drug sensitive platin testing antituberculotics sensitivety to mycobacterium tuberculosis.
Methods ToassesstheeffectivenessofSensititre tuberculosisdrugsensitiveplat , the
sensitivety of different antituberculotics ( isoniazid , rifampicin , ethambutol , streptomycin ,
levofloxacin , moxifloxacin , Amikacin , rifabutin , para aminosalicylic acid , ethionamide ,
cycloserine , kanamycin ) wastestedon124strainsofMycobacteriumtuberculosiscomplexfrom
clinicalisolatesbySensititretuberculosisdrugsensitiveplatorL-Jpropotionmethod.Results
Thesensitivityandspecifity ofSensititre tuberculosisdrugsensitiveplatintestingthe
antituberculoticssensitivety wereabout90.0% or more , which wascompared withtheL-J
proportionmethod.Conclusion TheeffectivenessofSensititretuberculosisdrugsensitiveplat
wasconsistentwiththatfromtheL-Jproportionmethod , butitshortenedthetestdurationand
wasmoreconvenient.Inaddition , Sensititretuberculosisdrugsensitiveplatcangetminimum
inhibitoryconcentrationsofthedifferentantituberculotics.
